Dentate Gyrus - Physiology
Research News and Information

Sunday, November 22, 2009

LTD induction suppresses LTP-induced hippocampal adult neurogenesis.

21 Sep 2009 Neurogenesis persists in certain adult brain regions including the dentate gyrus. Recent studies have shown that long-term potentiation (LTP) induction in the afferent pathway enhances adult neurogenesis in the dentate gyrus. Here, we investigated ... Read more...

NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory.

8 Sep 2009 The molecular underpinnings of exploration and its link to learning and memory remain poorly understood. Here we show that inducible, modest overexpression of neuronal calcium sensor 1 (Ncs1) selectively in the adult murine dentate gyrus (DG) ... Read more...

Nicotine's Allure.

8 Sep 2009 Both conscious and unconscious memory mechanisms contribute to the rewarding effects of nicotine and other drugs of abuse. In this issue of Neuron, Tang and Dani use in vivo measures of synaptic plasticity in freely moving mice to link ... Read more...

Latest indexed articles for 'Dentate Gyrus - Physiology'

These are the very latest articles for this heading:

• LTD induction suppresses LTP-induced hippocampal adult neurogenesis. 21 Sep 2009
• NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory. 8 Sep 2009
• Nicotine's Allure. 8 Sep 2009
• Beta oscillations and hippocampal place cell learning during exploration of novel environments. 30 Aug 2009
• Bilateral reorganization of the dentate gyrus in hippocampal sclerosis: a postmortem study. 24 Aug 2009
• Role of dentate gyrus in aligning internal spatial map to external landmark. 23 Aug 2009
• Stimulation of the nucleus raphe medialis modifies basal synaptic transmission at the dentate gyrus, but not long-term potentiation or its reinforcement by stimulation of the basolateral amygdala. 18 Aug 2009
• N-methyl-D-aspartate receptor independent changes in expression of polysialic acid-neural cell adhesion molecule despite blockade of homosynaptic long-term potentiation and heterosynaptic long-term depression in the awake freely behaving rat dentate gyrus. 11 Aug 2009
• Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis. 3 Aug 2009
• Activation of metabotropic glutamate receptor type 2/3 supports the involvement of the hippocampal mossy fiber pathway on contextual fear memory consolidation. 26 Jul 2009
• FGF2 modulates the voltage-dependent K+ current and changes excitability of rat dentate gyrus granule cells. 14 Jul 2009
• Is the dentate gyrus an independent generator of in vitro recorded theta rhythm? 13 Jul 2009
• A functional role for adult hippocampal neurogenesis in spatial pattern separation. 8 Jul 2009
• Reduced excitability in the dentate gyrus network of betaIV-spectrin mutant mice in vivo. 29 Jun 2009
• Hippocampus-dependent learning is associated with adult neurogenesis in MRL/MpJ mice. 29 Jun 2009
• Impaired in vivo synaptic plasticity in dentate gyrus and spatial memory in juvenile rats induced by prenatal morphine exposure. 29 Jun 2009
• Excitability changes within transverse lamellae of dentate granule cells and their longitudinal spread following orthodromic or antidromic activation. 29 Jun 2009
• Effects of carnosine on long-term plasticity of medial perforant pathway/dentate gyrus synapses in urethane-anesthetized rats: an in vivo model. 22 Jun 2009
• Conditional ablation and recovery of forebrain neurogenesis in the mouse. 18 Jun 2009
• Effect of postnatal methamphetamine trauma and adolescent methylphenidate treatment on adult hippocampal neurogenesis in gerbils. 15 Jun 2009

See a longer list of these articles.

Technical information about 'Dentate Gyrus'

Definition: Gray matter situated above the gyrus hippocampi. It is composed of three layers. The molecular layer is continuous with the HIPPOCAMPUS in the hippocampal fissure. The granular layer consists of closely arranged spherical or oval neurons, called granule cells, whose AXONS pass through the polymorphic layer ending on the DENDRITES of pyramidal cells in the hippocampus.

Descriptor UI: D018891

Alternative terms: Dentate Gyrus; Gyrus, Dentate; Gyrus Dentatus; Fascia Dentata; Dentata, Fascia; Dentate Fascia; Fascia, Dentate;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.464.405.200; A08.186.211.730.885.287.500.345.200;

History Note: 1996