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Deoxycytidine
Research News and Information

Sunday, March 21, 2010

Ceramide metabolism determines glioma cell resistance to chemotherapy.

29 Nov 2009 Tumor cell resistance to chemotherapy constitutes a major problem in the treatment of malignant tumors. We here investigated the role of ceramide metabolism for the resistance of glioma cells to treatment with the chemotherapeutic drug, gemcitabine. ... Read more...


CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells.

13 Nov 2009 Accumulating evidence suggests that tumors are composed of a heterogeneous cell population with a small subset of cancer stem cells (CSCs) that sustain tumor formation and growth. Recently, there have been efforts to explain drug resistance of ... Read more...


Phase II trial of thalidomide, irinotecan and gemcitabine in chemonaive patients with advanced non-small cell lung cancer.

30 Oct 2009 This study aim was to determine the efficacy and safety of the combination of Gemcitabine 1000 mg/m(2) day 1 & 8 and Irinotecan 100 mg/m(2) day 1 & 8 with escalating dose of thalidomide in chemonaive patients with advanced non-small cell lung ... Read more...

 

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Technical information about 'Deoxycytidine'

Chemical name: Cytidine, 2'-deoxy-

Registry Number: 951-77-9

Descriptor UI: D003841

Alternative terms: Deoxycytidine; CDR; Cytosine Deoxyribonucleoside; Deoxyribonucleoside, Cytosine; Cytosine Deoxyriboside; Deoxyriboside, Cytosine;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D03.383.742.680.245.500; D13.570.230.329; D13.570.685.245.500;

History Note: 75(73)

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