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Depressive Disorder - Physiopathology
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Definition of 'Depressive Disorder'

An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Common names: Depressive Disorder; Depressive Disorders; Disorder, Depressive; Disorders, Depressive; Neurosis, Depressive; Depressive Neuroses; Depressive Neurosis; Neuroses, Depressive; Depression, Endogenous; Depressions, Endogenous; Endogenous Depression; Endogenous Depressions; Depressive Syndrome

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Saturday, November 21, 2009

Erectile dysfunction, cardiovascular diseases and depression: interaction of therapy.

30 Aug 2009 Several studies have revealed the intimate associations between erectile dysfunction (ED), ischemic heart disease (IHD) and depression. Whether the physicians should also screen for the other two components when a patient presents with one component ... Read more...


Knockout of the norepinephrine transporter and pharmacologically diverse antidepressants prevent behavioral and brain neurotrophin alterations in two chronic stress models of depression.

16 Aug 2009 Diverse factors such as changes in neurotrophins and brain plasticity have been proposed to be involved in the actions of antidepressant drugs (ADs). However, in mouse models of depression based on chronic stress, it is still unclear whether ... Read more...


Computational modeling and empirical studies of hippocampal neurogenesis-dependent memory: Effects of interference, stress and depression.

Aug 2009 Prolonged stress causes dysregulation in the hypothalamic-pituitary-adrenal axis and may contribute to the pathogenesis of major depressive disorder (MDD). MDD is associated with pathological changes in several brain regions, particularly the ... Read more...

 

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Technical information about 'Depressive Disorder'

Definition: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Descriptor UI: D003866

Alternative terms: Depressive Disorder; Depressive Disorders; Disorder, Depressive; Disorders, Depressive; Neurosis, Depressive; Depressive Neuroses; Depressive Neurosis; Neuroses, Depressive; Depression, Endogenous; Depressions, Endogenous; Endogenous Depression; Endogenous Depressions; Depressive Syndrome; Depressive Syndromes; Syndrome, Depressive; Syndromes, Depressive; Depression, Neurotic; Depressions, Neurotic; Neurotic Depression; Neurotic Depressions; Melancholia; Melancholias; Unipolar Depression; Depression, Unipolar; Depressions, Unipolar; Unipolar Depressions;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; rehabilitation; surgery; therapy; urine; ultrasonography; virology;

Tree Number: F03.600.300;

Online Note: use ADJUSTMENT DISORDERS to search DEPRESSIVE NEUROSES 1969-80

History Note: 81; DEPRESSION, NEUROTIC was DEPRESSIVE NEUROSES see DEPRESSION, REACTIVE 1979-80, see under DEPRESSION, REACTIVE 1969-78

Technical Notes: do not confuse with DEPRESSION: see note there; depression lasting over 2 years = DYSTHYMIC DISORDER

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