Dermatitis, Atopic - Immunology
Research News and Information

Monday, November 23, 2009

Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13.

29 Sep 2009 BACKGROUND: Atopic dermatitis (AD) is characterized by local and systemic T(H)2 responses to cutaneously introduced allergens and is a risk factor for asthma. Blockade of T(H)2 cytokines has been suggested as therapy for AD. OBJECTIVES: We sought to ... Read more...

Expression of chemokines and chemokine receptors in lesional and nonlesional upper skin of patients with atopic dermatitis.

17 Sep 2009 BACKGROUND: Trafficking of dendritic cell (DC) subtypes to and from the skin plays a pivotal role in atopic dermatitis (AD). OBJECTIVES: We sought to determine the CCR pattern of epidermal DC subtypes and CCL expression in relation to the state of ... Read more...

Temporal dynamic changes of phenotypic expression of peripheral CD4 cells during environmental allergen challenge in an experimental model of canine atopic dermatitis: a pilot study.

30 Aug 2009 The immunopathology behind atopic dermatitis (AD) involves a myriad of inflammatory cells and their mediators. Thymus and activation-regulated chemokine (TARC) plays a significant role in the inflammatory phase by recruiting CCR4(+) T(H)2 cells. In ... Read more...

Latest indexed articles for 'Dermatitis, Atopic - Immunology'

These are the very latest articles for this heading:

• Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13. 29 Sep 2009
• Expression of chemokines and chemokine receptors in lesional and nonlesional upper skin of patients with atopic dermatitis. 17 Sep 2009
• Cyclosporin A reduces CD4(+)CD25(+) regulatory T-cell numbers in patients with atopic dermatitis. 17 Sep 2009
• Temporal dynamic changes of phenotypic expression of peripheral CD4 cells during environmental allergen challenge in an experimental model of canine atopic dermatitis: a pilot study. 30 Aug 2009
• The central role of Bcl-3 in atopic dermatitis. 30 Aug 2009
• Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum. 30 Aug 2009
• Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens. 30 Aug 2009
• Our evolving understanding of the functional role of filaggrin in atopic dermatitis. 30 Aug 2009
• Cytokine modulation of atopic dermatitis filaggrin skin expression. 30 Aug 2009
• Filaggrin in atopic dermatitis. 30 Aug 2009
• Different effects of pimecrolimus and betamethasone on the skin barrier in patients with atopic dermatitis. 30 Aug 2009
• Preface: The epidermal skin barrier: aspects of biology and dysfunction. 30 Aug 2009
• [Topical immune modulation and risk of cancer] 22 Aug 2009
• Modified proteins in allergy prevention. 17 Aug 2009
• Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response. 15 Aug 2009
• Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen. 6 Aug 2009
• Serum mucosa-associated epithelial chemokine (MEC/CCL28) in atopic dermatitis: a specific marker for severity. 30 Jul 2009
• Expansion of FOXP3-positive CD4+CD25+ T cells associated with disease activity in atopic dermatitis. 30 Jul 2009
• Filaggrin null mutations in childhood atopic dermatitis among the Chinese. 30 Jul 2009
• Immunology and skin disease 2009: frontiers in cutaneous immunology. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Dermatitis, Atopic'

Definition: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

Descriptor UI: D003876

Alternative terms: Dermatitis, Atopic; Atopic Dermatitides; Atopic Dermatitis; Dermatitides, Atopic; Neurodermatitis, Atopic; Atopic Neurodermatitides; Atopic Neurodermatitis; Neurodermatitides, Atopic; Neurodermatitis, Disseminated; Disseminated Neurodermatitides; Disseminated Neurodermatitis; Neurodermatitides, Disseminated; Eczema, Atopic; Atopic Eczema; Eczema, Infantile; Infantile Eczema;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C16.320.850.210; C17.800.174.193; C17.800.815.193; C17.800.827.210; C20.543.480.343;

Technical Notes: a type of immediate hypersensitivity