Dermis - Drug effects
Research News and Information

Sunday, March 21, 2010

Hydroxychloroquine induces autophagic cell death of human dermal fibroblasts: implications for treating fibrotic skin diseases.

29 Sep 2009 Hydroxychloroquine (HCQ) is widely used to treat rheumatic and inflammatory diseases. It inhibits inflammation by downregulating the effects of inflammatory cells and their mediators. Although HCQ has been used to treat several fibrotic skin ... Read more...

The effect of perfluorocarbon-based artificial oxygen carriers on tissue-engineered trachea.

30 Aug 2009 The biological effect of the perfluorocarbon-based artificial oxygen carrier (Oxygent) was investigated in tissue-engineered trachea (TET) construction. Media supplemented with and without 10% Oxygent were compared in all assessments. Partial tissue ... Read more...

Histatins enhance wound closure with oral and non-oral cells.

30 Aug 2009 The role of human saliva in oral wound-healing has never been fully elucidated. We previously demonstrated that parotid-salivary histatins enhance in vitro wound closure. The question remains whether other salivary-gland secretions enhance wound ... Read more...

Latest indexed articles for 'Dermis - Drug effects'

These are the very latest articles for this heading:

• Hydroxychloroquine induces autophagic cell death of human dermal fibroblasts: implications for treating fibrotic skin diseases. 29 Sep 2009
• The effect of perfluorocarbon-based artificial oxygen carriers on tissue-engineered trachea. 30 Aug 2009
• Histatins enhance wound closure with oral and non-oral cells. 30 Aug 2009
• Two distinct types of mouse melanocyte: differential signaling requirement for the maintenance of non-cutaneous and dermal versus epidermal melanocytes. 22 Jun 2009
• Synthesis and structure-activity relationships of radicicol derivatives and WNT-5A expression inhibitory activity. May 2009
• Radix clematidis extract inhibits UVB-induced MMP expression by suppressing the NF-kappaB pathway in human dermal fibroblasts. 29 Apr 2009
• Hydroxychloroquine modulates metabolic activity and proliferation and induces autophagic cell death of human dermal fibroblasts. 7 Apr 2009
• Evaluation of the in vitro skin permeation of antiviral drugs from penciclovir 1% cream and acyclovir 5% cream used to treat herpes simplex virus infection. 31 Mar 2009
• TW-37, a small-molecule inhibitor of Bcl-2, mediates S-phase cell cycle arrest and suppresses head and neck tumor angiogenesis. 30 Mar 2009
• l-Ascorbic acid 2-phosphate promotes elongation of hair shafts via the secretion of insulin-like growth factor-1 from dermal papilla cells through phosphatidylinositol 3-kinase. 24 Mar 2009
• alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma? 30 Jan 2009
• Low oxygen consumption and high body content of catch connective tissue contribute to low metabolic rate of sea cucumbers. 30 Jan 2009
• Investigation of the dermal sensitizing potential of traditional medical extracts in local lymph node assays. 12 Jan 2009
• Effect of aged garlic extract on wound healing: a new frontier in wound management. 30 Dec 2008
• Autonomic fiber sprouting in the skin in chronic inflammation. 12 Nov 2008
• Mesotherapy for skin rejuvenation: assessment of the subepidermal low-echogenic band by ultrasound evaluation with cross-sectional B-mode scanning. 30 Oct 2008
• Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes. 16 Sep 2008
• Dermal and epidermal remodeling using botulinum toxin type A for facial, non reducible, hyperkinetic lines: two case studies. 30 Aug 2008
• The role of the epidermis in the control of scarring: evidence for mechanism of action for silicone gel. 21 Jul 2008
• Ultraviolet A induces transport of compatible organic osmolytes in human dermal fibroblasts. 12 Jun 2008

See a longer list of these articles.

Technical information about 'Dermis'

Definition: A layer of vascularized connective tissue underneath the EPIDERMIS. The surface of the dermis contains innervated papillae. Embedded in or beneath the dermis are SWEAT GLANDS; HAIR FOLLICLES; and SEBACEOUS GLANDS.

Descriptor UI: D020405

Alternative terms: Dermis; Corium;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A17.815.180;

History Note: 99