Dextrans - Pharmacology
Research News and Information

Sunday, November 22, 2009

Polymer-conjugated guanidine is a potentially useful anti-tumor agent.

30 Jul 2009 Guanidine compounds have important biochemical properties. Aminoguanidine, as an example, is an anti-oxidant, a nitric oxide synthase inhibitor (NOS) which prevents nitric oxide formation, and an inhibitor of advanced glycosylation end products ... Read more...

The potential protective effect of low potassium dextran against lipid peroxidation in a rat lung transplantation model.

21 Jul 2009 The overproduction of reactive oxygen species plays an important role in the cascade of events during lung ischemia-reperfusion leading to graft failure. An evaluation of the peripheral markers of oxidative stress and antioxidant enzyme activities ... Read more...

Techniques for time-efficient isolation of human skin dendritic cell subsets and assessment of their antigen uptake capacity.

30 Jun 2009 Dendritic cells (DCs) residing in skin are important sentinels for foreign antigens. Methods to facilitate studies of subsets of skin DCs are important to increase the understanding of various pathogens, allergens, topical treatments or vaccine ... Read more...

Latest indexed articles for 'Dextrans - Pharmacology'

These are the very latest articles for this heading:

• Polymer-conjugated guanidine is a potentially useful anti-tumor agent. 30 Jul 2009
• The potential protective effect of low potassium dextran against lipid peroxidation in a rat lung transplantation model. 21 Jul 2009
• Techniques for time-efficient isolation of human skin dendritic cell subsets and assessment of their antigen uptake capacity. 30 Jun 2009
• A novel approach for enhancing the catalytic efficiency of a protease at low temperature: reduction in substrate inhibition by chemical modification. 29 Jun 2009
• Measurement of solute transport in the endothelial glycocalyx using indicator dilution techniques. 22 Jun 2009
• Optimizing the deswelling process of organ-cultured corneas. 30 May 2009
• Effect of dextran 500 on radial migration of erythrocytes in postcapillary venules at low flow rates. 30 May 2009
• Effects of maleimide-polyethylene glycol-modified human hemoglobin (MP4) on tissue necrosis in SKH1-hr hairless mice. 15 Mar 2009
• Omentum facilitates liver regeneration. 5 Mar 2009
• Kinematic viscosity of therapeutic pulmonary surfactants with added polymers. 27 Feb 2009
• The diagonal band of Broca is involved in the pressor pathway activated by noradrenaline microinjected into the periaqueductal gray area of rats. 31 Jan 2009
• Comparative studies on the mechanisms of action of four polysaccharides on arterial restenosis. 30 Dec 2008
• Red blood cell aggregation: 45 years being curious. 30 Dec 2008
• The effects of nonionic polymers on thyroid stimulation and TSH receptor binding by the human monoclonal TSH receptor autoantibody M22. 30 Dec 2008
• Enhancement of the biological activity of BMP-2 by synthetic dextran derivatives. 30 Dec 2008
• Comparative study of the in vitro effect of nanoliposomes with oxidized dextrans on peritoneal cells. 29 Nov 2008
• In vitro effect of oxidized dextrans on peritoneal cells. 29 Nov 2008
• Structural changes in the liver parenchyma and granulomas of mice with chronic BCG granulomatosis during therapy with composition of isoniazid and dialdehyde dextran. 29 Nov 2008
• Effect of dialdehyde dextran on structural changes in the liver and lungs during chronic BCG granulomatosis. 29 Nov 2008
• Therapeutic efficacy of a composition of amphotericin B and dialdehyde dextran in kidney damage in mice of various strains with systemic candidiasis. 29 Nov 2008

See a longer list of these articles.

Technical information about 'Dextrans'

Definition: A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.

Registry Number: 9004-54-0

Descriptor UI: D003911

Alternative terms: Dextrans; Rheopolyglucin; Dextran; Dextran 40; Dextran 40000; Dextran 70; Dextran 75; Dextran 80; Dextran B-1355-S; Dextran B 1355 S; Dextran B1355; Dextran B-1355; Dextran B 1355; Dextran B512; Dextran M 70; Dextran T 70; Dextran T-40; Dextran T 40; Dextran T-500; Dextran T 500; Hemodex; Hyskon; Infukoll; Macrodex; Polyglucin; Promit; Rheodextran; Rheoisodex; Rheomacrodex; Rondex; Saviosol;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; ultrastructure;

Pharmacological Action: Anticoagulants; Plasma Substitutes;

Tree Number: D05.750.078.562.272; D09.698.365.272;

Online Note: use DEXTRANS to search DEXTRAN 1966-78

History Note: 79; was DEXTRAN 1963-78