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Dextrans
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Definition of 'Dextrans'

A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.

Common names: Dextrans; Rheopolyglucin; Dextran; Dextran 40; Dextran 40000; Dextran 70; Dextran 75; Dextran 80; Dextran B-1355-S; Dextran B 1355 S; Dextran B1355; Dextran B-1355; Dextran B 1355; Dextran B512; Dextran M 70; Dextran T 70; Dextran T-40; Dextran T 40; Dextran T-500; Dextran T 500; Hemodex; Hyskon

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Saturday, November 21, 2009

Antitumor activity of delimotecan against human metastatic melanoma: pharmacokinetics and molecular determinants.

13 Nov 2009 Delimotecan (MEN 4901/T-0128) is a new cytotoxic prodrug constituted by a camptothecin analog (T-2513) bound to carboxymethyl dextran through a triglycine linker. A significant antitumor activity of delimotecan against human metastatic melanoma ... Read more...


Retinal ganglion cells in the eastern newt Notophthalmus viridescens: topography, morphology, and diversity.

18 Oct 2009 The topography and morphology of retinal ganglion cells (RGCs) in the eastern newt were studied. Cells were retrogradely labeled with tetramethylrhodamine-conjugated dextran amines or horseradish peroxidase and examined in retinal wholemounts. Their ... Read more...


Tissue responses to novel tissue engineering biodegradable cryogel scaffolds: an animal model.

29 Sep 2009 Biodegradable macroporous cryogels with highly open and interconnected pore structures were produced from dextran modified with oligo L-lactide bearing hydroxyethylmethacrylate (HEMA) end groups in moderately frozen solutions. Tissue responses to ... Read more...

 

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Technical information about 'Dextrans'

Definition: A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.

Registry Number: 9004-54-0

Descriptor UI: D003911

Alternative terms: Dextrans; Rheopolyglucin; Dextran; Dextran 40; Dextran 40000; Dextran 70; Dextran 75; Dextran 80; Dextran B-1355-S; Dextran B 1355 S; Dextran B1355; Dextran B-1355; Dextran B 1355; Dextran B512; Dextran M 70; Dextran T 70; Dextran T-40; Dextran T 40; Dextran T-500; Dextran T 500; Hemodex; Hyskon; Infukoll; Macrodex; Polyglucin; Promit; Rheodextran; Rheoisodex; Rheomacrodex; Rondex; Saviosol;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; ultrastructure;

Pharmacological Action: Anticoagulants; Plasma Substitutes;

Tree Number: D05.750.078.562.272; D09.698.365.272;

Online Note: use DEXTRANS to search DEXTRAN 1966-78

History Note: 79; was DEXTRAN 1963-78

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