Diabetes Mellitus - Metabolism
Research News and Information

Sunday, November 22, 2009

beta-Cell-specific overexpression of glutathione peroxidase preserves intranuclear MafA and reverses diabetes in db/db mice.

7 Oct 2009 Chronic hyperglycemia causes oxidative stress, which contributes to damage in various tissues and cells, including pancreatic beta-cells. The expression levels of antioxidant enzymes in the islet are low compared with other tissues, rendering the ... Read more...

Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart.

2 Sep 2009 Vasodilator-stimulated phosphoprotein (VASP) is a major substrate for cyclic nucleotide-dependent kinases that has been implicated in cardiac pathology, yet many aspects of VASP's molecular regulation in cardiomyocytes are incompletely understood. ... Read more...

[Poor bone quality in diabetes and arterioscelerosis]

30 Aug 2009 Type 1 and 2 diabetes deteriorate bone quality in terms of collagen cross-links formation in bone, Recently, we demonstrate that hyperhomocysteinemia also resulted in collagen cross-link abnormalities in bone (Saito M, Osteoporos Int, 2009 in press) ... Read more...

Latest indexed articles for 'Diabetes Mellitus - Metabolism'

These are the very latest articles for this heading:

• beta-Cell-specific overexpression of glutathione peroxidase preserves intranuclear MafA and reverses diabetes in db/db mice. 7 Oct 2009
• Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart. 2 Sep 2009
• [Poor bone quality in diabetes and arterioscelerosis] 30 Aug 2009
• [Overview: derangement of bone metabolism in diabetes mellitus] 30 Aug 2009
• Methylglyoxal: possible link between hyperglycaemia and immune suppression? 22 Aug 2009
• Diabetes changes the levels of ionotropic glutamate receptors in the rat retina. 15 Aug 2009
• Bibliography. Current world literature. 30 Jul 2009
• The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues. 26 Jul 2009
• Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice. 21 Jul 2009
• The importance of brown adipose tissue. 21 Jul 2009
• Diabetes mellitus is associated with increased intramyocellular triglyceride, but not diglyceride, content in obese humans. 14 Jul 2009
• Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion. 13 Jul 2009
• Succination of thiol groups in adipose tissue proteins in diabetes: succination inhibits polymerization and secretion of adiponectin. 8 Jul 2009
• Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes. 8 Jul 2009
• Altered metabolism of copper, zinc, and magnesium is associated with increased levels of glycated hemoglobin in patients with diabetes mellitus. 7 Jul 2009
• Serum high-molecular weight adiponectin decreases abruptly after an oral glucose load in subjects with normal glucose tolerance or impaired fasting glucose, but not those with impaired glucose tolerance or diabetes mellitus. 7 Jul 2009
• Incidence and prevalence of CIDP and the association of diabetes mellitus. 5 Jul 2009
• Shiftwork and impaired glucose metabolism: a 14-year cohort study on 7104 male workers. 29 Jun 2009
• A comparison of diabetes learning with and without interactive multimedia to improve knowledge, control, and self-care among people with diabetes in Taiwan. 29 Jun 2009
• A combined crystalloid and colloid pd solution as a glucose-sparing strategy for volume control in high-transport apd patients: a prospective multicenter study. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Diabetes Mellitus'

Definition: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Descriptor UI: D003920

Alternative terms: Diabetes Mellitus;

Related Mesh Headings: Diabetes Insipidus; Diabetic Diet; Prediabetic State; Scleredema Adultorum; Glycosylation End Products, Advanced; Glucose Intolerance; Gastroparesis;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C18.452.394.750; C19.246;

Technical Notes: GEN or unspecified; prefer specifics; pregnancy of diabetic patients = PREGNANCY IN DIABETICS but do not confuse with DIABETES, GESTATIONAL: see note there; PREDIABETIC STATE is also available & includes subclinical diabetes; /diet ther: consider coord with DIABETIC DIET but see note there; alloxan- & streptozocin-induced diabetes: see note on DIABETES MELLITUS, EXPERIMENTAL