Diabetes Mellitus, Experimental - Drug therapy
Research News and Information

Saturday, November 21, 2009

Loss of arterial and renal nitric oxide bioavailability in hypertensive rats with diabetes: effect of beta-blockers.

Sep 2009 BACKGROUND: Endothelial cell (EC) dysfunction contributes to hypertension and mechanisms of atherosclerosis. Agents that improve EC function may provide vascular protection, especially in patients with multiple risk factors. In this study, we ... Read more...

Ghrelin reverses experimental diabetic neuropathy in mice.

Sep 2009 Ghrelin, an acylated peptide produced in the stomach, increases food intake and growth hormone secretion, suppresses inflammation and oxidative stress, and promotes cell survival and proliferation. We investigated the pharmacological potential of ... Read more...

Stealth nanoparticles coated with heparin as peptide or protein carriers.

30 Aug 2009 Nanoparticles (prepared from a mixture of polyester and a polycationic polymer) loaded with insulin were prepared by a double emulsion method followed by evaporation solvent. Low molecular weight heparin (LMWH) was bound by electrostatic ... Read more...

Latest indexed articles for 'Diabetes Mellitus, Experimental - Drug therapy'

These are the very latest articles for this heading:

• Loss of arterial and renal nitric oxide bioavailability in hypertensive rats with diabetes: effect of beta-blockers. Sep 2009
• Ghrelin reverses experimental diabetic neuropathy in mice. Sep 2009
• Stealth nanoparticles coated with heparin as peptide or protein carriers. 30 Aug 2009
• Activation of the PDK-1/Akt/eNOS pathway involved in aortic endothelial function differs between hyperinsulinemic and insulin-deficient diabetic rats. 26 Aug 2009
• Molecular mechanisms of tungstate-induced pancreatic plasticity: a transcriptomics approach. 26 Aug 2009
• Antidiabetic and antilipidemic effect of eremanthin from Costus speciosus (Koen.)Sm., in STZ-induced diabetic rats. 16 Aug 2009
• Anti-diabetic properties of three common Bidens pilosa variants in Taiwan. 12 Aug 2009
• Effects of grape seed extract and its ethylacetate/ethanol fraction on blood glucose levels in a model of type 2 diabetes. 30 Jul 2009
• Amelioration of metformin-induced hypothyroidism by Withania somnifera and Bauhinia purpurea extracts in Type 2 diabetic mice. 30 Jul 2009
• Pycnogenol efficiency on glycaemia, motor nerve conduction velocity and markers of oxidative stress in mild type diabetes in rats. 30 Jul 2009
• Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. 24 Jul 2009
• Dimethylthiourea normalizes velocity-dependent, but not force-dependent, index of ventricular performance in diabetic rats: role of myosin heavy chain isozyme. 22 Jul 2009
• Attenuation of renoinflammatory cascade in experimental model of diabetic nephropathy by sesamol. 20 Jul 2009
• An adiponectin-like molecule with antidiabetic properties. 14 Jul 2009
• Prevention of early loss of transplanted islets in the liver of mice by adenosine. 13 Jul 2009
• Breviscapine ameliorates hypertrophy of cardiomyocytes induced by high glucose in diabetic rats via the PKC signaling pathway. 11 Jul 2009
• Antihyperglycemic and antioxidative potential of hydroalcoholic extract of Butea monosperma Lam flowers in alloxan-induced diabetic mice. 29 Jun 2009
• Antihyperglycemic, antihyperlipidemic and antioxidant effects of Dihar, a polyherbal ayurvedic formulation in streptozotocin induced diabetic rats. 29 Jun 2009
• Dietary quercetin alleviates diabetic symptoms and reduces streptozotocin-induced disturbance of hepatic gene expression in mice. 29 Jun 2009
• Supplementation with magnesium and vitamin E were more effective than magnesium alone to decrease plasma lipids and blood viscosity in diabetic rats. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Diabetes Mellitus, Experimental'

Definition: Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.

Descriptor UI: D003921

Alternative terms: Diabetes Mellitus, Experimental; Experimental Diabetes Mellitus; Streptozotocin Diabetes; Diabetes, Streptozotocin; Streptozocin Diabetes; Diabete, Streptozocin; Diabetes, Streptozocin; Streptozocin Diabete; Alloxan Diabetes; Diabetes, Alloxan;

Related Mesh Headings: Mice, Inbred NOD;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; surgery; therapy; transmission; urine; ultrasonography; virology;

Tree Number: C18.452.394.750.074; C19.246.240; E05.598.500.374;

Online Note: use DIABETES MELLITUS, EXPERIMENTAL to search ALLOXAN DIABETES 1966-77

History Note: 78; ALLOXAN DIABETES was heading 1963-77

Technical Notes: index alloxan or streptozocin diabetes as DIABETES MELLITUS, EXPERIMENTAL (IM) + ALLOXAN or STREPTOZOCIN (NIM) only if the chem are particularly discussed; probably in animal so do not use /vet but don't forget check tag ANIMALS; DF: DIABETES MELLITUS EXPER