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Diabetes Mellitus, Type 1 - Complications
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Definition of 'Diabetes Mellitus, Type 1'

A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

Common names: Diabetes Mellitus, Type 1; Diabetes Mellitus, Insulin-Dependent; Diabetes Mellitus, Insulin Dependent; Insulin-Dependent Diabetes Mellitus; Diabetes Mellitus, Juvenile-Onset; Diabetes Mellitus, Juvenile Onset; Juvenile-Onset Diabetes Mellitus; Type 1 Diabetes Mellitus

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Saturday, November 21, 2009

Dry eye reversal and corneal sensation restoration with topical naltrexone in diabetes mellitus.

30 Oct 2009 OBJECTIVE: To determine if topical application of naltrexone hydrochloride (NTX), an opioid antagonist, restores tear production and corneal sensation in rats with diabetes mellitus. METHODS: Type 1 diabetes was induced with streptozotocin in rats. ... Read more...


Early progression of the autonomic dysfunction observed in pediatric type 1 diabetes mellitus.

3 Oct 2009 To focus on early cardiac and vascular autonomic dysfunction that might complicate type 1 diabetes mellitus in children, we planned an observational, cross-sectional study in a population of 93 young patients, under insulin treatment, subdivided in ... Read more...


Diabetic microangiopathy in the liver: an autopsy study of incidence and association with other diabetic complications.

29 Sep 2009 Diabetic hepatosclerosis (DH) is a recently described form of diabetic microangiopathy with hepatic sinusoidal fibrosis and basement membrane deposition without cirrhosis. The objective was to investigate the frequency of DH and its correlation with ... Read more...

 

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Technical information about 'Diabetes Mellitus, Type 1'

Definition: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

Descriptor UI: D003922

Alternative terms: Diabetes Mellitus, Type 1; Diabetes Mellitus, Insulin-Dependent; Diabetes Mellitus, Insulin Dependent; Insulin-Dependent Diabetes Mellitus; Diabetes Mellitus, Juvenile-Onset; Diabetes Mellitus, Juvenile Onset; Juvenile-Onset Diabetes Mellitus; Type 1 Diabetes Mellitus; Diabetes Mellitus, Sudden-Onset; Diabetes Mellitus, Sudden Onset; Mellitus, Sudden-Onset Diabetes; Sudden-Onset Diabetes Mellitus; Diabetes Mellitus, Type I; IDDM; Diabetes Mellitus, Brittle; Brittle Diabetes Mellitus; Diabetes Mellitus, Ketosis-Prone; Diabetes Mellitus, Ketosis Prone; Ketosis-Prone Diabetes Mellitus; Diabetes, Autoimmune; Autoimmune Diabete; Diabete, Autoimmune; Autoimmune Diabetes;

Related Mesh Headings: Mice, Inbred NOD;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C18.452.394.750.124; C19.246.267; C20.111.327;

History Note: 2005 (1984)

Technical Notes: MICE, INBRED NOD are a common model for this disease

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