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Diabetes Mellitus, Type 1 - Physiopathology
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Definition of 'Diabetes Mellitus, Type 1'

A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

Common names: Diabetes Mellitus, Type 1; Diabetes Mellitus, Insulin-Dependent; Diabetes Mellitus, Insulin Dependent; Insulin-Dependent Diabetes Mellitus; Diabetes Mellitus, Juvenile-Onset; Diabetes Mellitus, Juvenile Onset; Juvenile-Onset Diabetes Mellitus; Type 1 Diabetes Mellitus

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Saturday, November 21, 2009

Reversing bacteria-induced vitamin D receptor dysfunction is key to autoimmune disease.

30 Aug 2009 Vitamin D research is discussed in light of the hypothesis that the lower average levels of vitamin D frequently observed in autoimmune disease are not a sign of deficiency. Instead, it is proposed that the lower levels result from chronic infection ... Read more...


Bone mineral density, osteocalcin, and bone-specific alkaline phosphatase in patients with insulin-dependent diabetes mellitus.

30 Aug 2009 The aims of this study were to evaluate the prevalence of osteopenia and the relationships between osteocalcin (OC), bone alkaline phosphatase (bALP), and bone mineral density (BMD) in patients with insulin-dependent diabetes mellitus (IDDM). A ... Read more...


The relation of markers of inflammation and endothelial dysfunction to the prevalence and progression of diabetic retinopathy: Wisconsin epidemiologic study of diabetic retinopathy.

30 Aug 2009 OBJECTIVE: To determine the relation of glycemia, blood pressure, and serum total cholesterol level as systemic markers of inflammation and endothelial dysfunction to the prevalence and incidence of diabetic retinal outcomes in persons with ... Read more...

 

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Technical information about 'Diabetes Mellitus, Type 1'

Definition: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

Descriptor UI: D003922

Alternative terms: Diabetes Mellitus, Type 1; Diabetes Mellitus, Insulin-Dependent; Diabetes Mellitus, Insulin Dependent; Insulin-Dependent Diabetes Mellitus; Diabetes Mellitus, Juvenile-Onset; Diabetes Mellitus, Juvenile Onset; Juvenile-Onset Diabetes Mellitus; Type 1 Diabetes Mellitus; Diabetes Mellitus, Sudden-Onset; Diabetes Mellitus, Sudden Onset; Mellitus, Sudden-Onset Diabetes; Sudden-Onset Diabetes Mellitus; Diabetes Mellitus, Type I; IDDM; Diabetes Mellitus, Brittle; Brittle Diabetes Mellitus; Diabetes Mellitus, Ketosis-Prone; Diabetes Mellitus, Ketosis Prone; Ketosis-Prone Diabetes Mellitus; Diabetes, Autoimmune; Autoimmune Diabete; Diabete, Autoimmune; Autoimmune Diabetes;

Related Mesh Headings: Mice, Inbred NOD;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C18.452.394.750.124; C19.246.267; C20.111.327;

History Note: 2005 (1984)

Technical Notes: MICE, INBRED NOD are a common model for this disease

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