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Diabetes Mellitus, Type 1
Research News and Information
Definition of 'Diabetes Mellitus, Type 1'A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. Common names: Diabetes Mellitus, Type 1; Diabetes Mellitus, Insulin-Dependent; Diabetes Mellitus, Insulin Dependent; Insulin-Dependent Diabetes Mellitus; Diabetes Mellitus, Juvenile-Onset; Diabetes Mellitus, Juvenile Onset; Juvenile-Onset Diabetes Mellitus; Type 1 Diabetes Mellitus |
Saturday, November 21, 2009
Prediction of proliferative diabetic retinopathy with hemoglobin level.
30 Oct 2009 
OBJECTIVE: To investigate the role of hemoglobin (HGB) level in predicting proliferative diabetic retinopathy (PDR). METHODS: We assessed 426 individuals without PDR at baseline (213 men; 213 women) from the Pittsburgh Epidemiology of Diabetes ... Read more...
Dry eye reversal and corneal sensation restoration with topical naltrexone in diabetes mellitus.
30 Oct 2009 OBJECTIVE: To determine if topical application of naltrexone hydrochloride (NTX), an opioid antagonist, restores tear production and corneal sensation in rats with diabetes mellitus. METHODS: Type 1 diabetes was induced with streptozotocin in rats. ... Read more...
30 Oct 2009 Insulin is a critical autoantigen for the development of autoimmune diabetes in non-obese diabetic (NOD) mice. About 80% of NOD females and 30-40% of NOD males develop diabetes. However, Insulin2 (Ins2) knockout NOD mice develop autoimmune diabetes ... Read more...
Latest indexed articles for 'Diabetes Mellitus, Type 1'
These are the very latest articles for this heading:
- Images in clinical medicine. Injection-site lipoatrophy.
3 Nov 2009 - Prediction of proliferative diabetic retinopathy with hemoglobin level. 30 Oct 2009
- Dry eye reversal and corneal sensation restoration with topical naltrexone in diabetes mellitus. 30 Oct 2009
- Insulin2 gene (Ins2) transcription by NOD bone marrow-derived cells does not influence autoimmune diabetes development in NOD-Ins2 knockout mice. 30 Oct 2009
- Is antigen specificity of autoreactive T cells the key to islet entry? 14 Oct 2009
- Autoimmunity during thymectomy-induced lymphopenia: role of thymus ablation and initial effector T cell activation timing in nonobese diabetic mice. 13 Oct 2009
- Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion. 13 Oct 2009
- Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone. 10 Oct 2009
- Gene therapy with neurogenin 3 and betacellulin reverses major metabolic problems in insulin-deficient diabetic mice. 7 Oct 2009
- T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event. 6 Oct 2009
- How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets. 6 Oct 2009
- Early progression of the autonomic dysfunction observed in pediatric type 1 diabetes mellitus. 3 Oct 2009
- Diabetes and the public's health. Oct 2009
- Reply to: "Experimental aspects of copy number variant assays at CCL3L1". 29 Sep 2009
- Experimental aspects of copy number variant assays at CCL3L1. 29 Sep 2009
- CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice. 29 Sep 2009
- A better future for children with type 1 diabetes: Review of the conclusions from the Diabetes Control and Complications Trial and the Epidemiology of Diabetes Interventions and Complications study. 29 Sep 2009
- Current advances and travails in islet transplantation. 29 Sep 2009
- Relation between low-density lipoprotein particle size and insulin and diabetes mellitus. 29 Sep 2009
- Renal and retinal effects of enalapril and losartan in type 1 diabetes. 29 Sep 2009
See a longer list of these articles.
Technical information about 'Diabetes Mellitus, Type 1'
Definition: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
Descriptor UI: D003922
Alternative terms: Diabetes Mellitus, Type 1; Diabetes Mellitus, Insulin-Dependent; Diabetes Mellitus, Insulin Dependent; Insulin-Dependent Diabetes Mellitus; Diabetes Mellitus, Juvenile-Onset; Diabetes Mellitus, Juvenile Onset; Juvenile-Onset Diabetes Mellitus; Type 1 Diabetes Mellitus; Diabetes Mellitus, Sudden-Onset; Diabetes Mellitus, Sudden Onset; Mellitus, Sudden-Onset Diabetes; Sudden-Onset Diabetes Mellitus; Diabetes Mellitus, Type I; IDDM; Diabetes Mellitus, Brittle; Brittle Diabetes Mellitus; Diabetes Mellitus, Ketosis-Prone; Diabetes Mellitus, Ketosis Prone; Ketosis-Prone Diabetes Mellitus; Diabetes, Autoimmune; Autoimmune Diabete; Diabete, Autoimmune; Autoimmune Diabetes;
Related Mesh Headings: Mice, Inbred NOD;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C18.452.394.750.124; C19.246.267; C20.111.327;
History Note: 2005 (1984)
Technical Notes: MICE, INBRED NOD are a common model for this disease