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Diabetic Foot - Genetics
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Definition of 'Diabetic Foot'

Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.

Common names: Diabetic Foot; Foot, Diabetic; Diabetic Feet; Feet, Diabetic; Foot Ulcer, Diabetic

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Sunday, March 14, 2010

Heat-shock protein 70 gene polymorphism is associated with the severity of diabetic foot ulcer and the outcome of surgical treatment.

29 Sep 2009 BACKGROUND: Foot ulcer is a significant cause of morbidity in diabetics. Genetic make-up can determine inflammatory and healing responses. This study examined the hypothesis that specific polymorphisms of the heat-shock protein 70 gene could ... Read more...


[Hyperbaric oxygen therapy of angiopathic changes in patients with inherited gene imbalance]

30 Oct 2007 INTRODUCTION: Phenotype match inherited by genes is in most cases present in monozygotic twins. Their phenotypic resemblance is unfortunately characterized by strong susceptibility for the development of chronic non-infectious diseases. One of the ... Read more...


Expression of apoptosis- and cell cycle-related proteins in epidermis of venous leg and diabetic foot ulcers.

30 Jul 2003 BACKGROUND: Epithelialization of cutaneous ulcers is a long-lasting process. To study the pathomechanism of impaired epithelialization, we evaluated the role of cell cycle- and apoptosis-related proteins in the regenerating epidermis. We ... Read more...

 

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Technical information about 'Diabetic Foot'

Definition: Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.

Descriptor UI: D017719

Alternative terms: Diabetic Foot; Foot, Diabetic; Diabetic Feet; Feet, Diabetic; Foot Ulcer, Diabetic;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C14.907.320.191; C17.800.893.592.450.200; C19.246.099.500.191; C19.246.099.937.250;

History Note: 94

Technical Notes: coordinate IM with specific type of diabetes mellitus (IM) if pertinent

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