Diabetic Nephropathies - Drug therapy
Research News and Information

Sunday, November 22, 2009

Cost-effectiveness of aliskiren in type 2 diabetes, hypertension, and albuminuria.

15 Sep 2009 The Aliskiren in the Evaluation of Proteinuria in Diabetes (AVOID) trial demonstrated that adding aliskiren, an oral direct renin inhibitor, at a dosage of 300 mg/d to the highest approved dosage of losartan and optimal antihypertensive therapy ... Read more...

The value of irbesartan in the management of hypertension.

30 Jul 2009 Elevated blood pressure levels are highly prevalent and are a major reason for cardiovascular events and thus place a significant financial burden on healthcare systems worldwide. Guidelines recommend five first-line anti-hypertensive drug classes, ... Read more...

Association of secondary hyperparathyroidism with CKD progression, health care costs and survival in diabetic predialysis CKD patients.

8 Jul 2009 BACKGROUND/AIMS: The objective of this study was to examine health care costs and utilization and the risks of dialysis or mortality among diabetic predialysis chronic kidney disease (CKD) patients with and without secondary hyperparathyroidism ... Read more...

Latest indexed articles for 'Diabetic Nephropathies - Drug therapy'

These are the very latest articles for this heading:

• Cost-effectiveness of aliskiren in type 2 diabetes, hypertension, and albuminuria. 15 Sep 2009
• Adequate vascular repair is relevant to improving renal perfusion and function following vasodilators in normoalbuminuric type 2 diabetic nephropathy. 30 Aug 2009
• The value of irbesartan in the management of hypertension. 30 Jul 2009
• Association of secondary hyperparathyroidism with CKD progression, health care costs and survival in diabetic predialysis CKD patients. 8 Jul 2009
• Angiotensin-receptor blockers in the prevention or treatment of microalbuminuria. 5 Jul 2009
• Pirfenidone is renoprotective in diabetic kidney disease. 30 Jun 2009
• Diabetes: Renal benefits of lowering BP in the absence of hypertension. 29 Jun 2009
• Effect of red wine on urinary protein, 8-hydroxydeoxyguanosine, and liver-type fatty acid-binding protein excretion in patients with diabetic nephropathy. 16 Jun 2009
• Gabapentin-induced rhabdomyolysis in a patient with diabetic neuropathy. 13 Jun 2009
• Tubular and glomerular injury in diabetes and the impact of ACE inhibition. 3 Jun 2009
• The biochemical pharmacology of renin inhibitors: implications for translational medicine in hypertension, diabetic nephropathy and heart failure: expectations and reality. 25 May 2009
• [Effect of pentoxifylline on the evolution of diabetic nephropathy] 20 May 2009
• Reduction of renal superoxide dismutase in progressive diabetic nephropathy. 19 May 2009
• Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: three randomized trials. 16 May 2009
• Long-term treatment of sirolimus but not cyclosporine ameliorates diabetic nephropathy in the rat. 13 May 2009
• The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential. 3 May 2009
• The amelioration of streptozotocin diabetes-induced renal damage by Wu-Ling-San (Hoelen Five Herb Formula), a traditional Chinese prescription. May 2009
• Effects of dual blockade of renin-angiotensin system in type 2 diabetes mellitus patients with diabetic nephropathy. 29 Apr 2009
• Early nephropathy in type 1 diabetes: the importance of early renal function decline. 29 Apr 2009
• Effects of alpha-lipoic acid on transforming growth factor beta1-p38 mitogen-activated protein kinase-fibronectin pathway in diabetic nephropathy. 29 Apr 2009

See a longer list of these articles.

Technical information about 'Diabetic Nephropathies'

Definition: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.

Descriptor UI: D003928

Alternative terms: Diabetic Nephropathies; Nephropathies, Diabetic; Nephropathy, Diabetic; Diabetic Nephropathy; Diabetic Kidney Disease; Diabetic Kidney Diseases; Kidney Disease, Diabetic; Kidney Diseases, Diabetic; Diabetic Glomerulosclerosis; Kimmelstiel-Wilson Syndrome; Kimmelstiel Wilson Syndrome; Syndrome, Kimmelstiel-Wilson; Kimmelstiel-Wilson Disease; Kimmelstiel Wilson Disease; Nodular Glomerulosclerosis; Glomerulosclerosis, Nodular; Glomerulosclerosis, Diabetic; Intracapillary Glomerulosclerosis;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C12.777.419.192; C13.351.968.419.192; C19.246.099.875;

Online Note: use DIABETIC NEPHROPATHIES to search KIMMELSTIEL-WILSON SYNDROME 1966-76

History Note: 65(64); KIMMELSTIEL-WILSON SYNDROME was heading 1963-76

Technical Notes: coord IM with specific kidney dis (IM); do not confuse with DIABETES INSIPIDUS, NEPHROGENIC, a form of diabetes insipidus