Disaccharides - Chemistry
Research News and Information

Monday, November 23, 2009

Glycan bioengineering in immunogen design for tumor T antigen immunotargeting.

30 Aug 2009 Bioengineering of Galbeta3GalNAcalpha, known as Thomsen-Friedenreich disaccharide (TFD), is studied to promote glycan immunogenicity and immunotargeting to tumor T antigen (Galbeta3GalNAcalpha-O-Ser/Thr). Theoretical studies on disaccharide ... Read more...

Freeze-dry microscopy of protein/sugar mixtures: drying behavior, interpretation of collapse temperatures and a comparison to corresponding glass transition data.

30 Aug 2009 The purpose of this study is to investigate the change in collapse appearance and temperature of protein/sugar mixtures as a function of nucleation temperature (T(n)), sublimation velocity (V(sub)) and the sugar/protein mole ratio when performing ... Read more...

Thermal denaturation of myoglobin in water--disaccharide matrixes: relation with the glass transition of the system.

18 Aug 2009 Proteins embedded in glassy saccharide systems are protected against adverse environmental conditions [Crowe et al. Annu. Rev. Physiol. 1998, 60, 73-103]. To further characterize this process, we studied the relationship between the glass transition ... Read more...

Latest indexed articles for 'Disaccharides - Chemistry'

These are the very latest articles for this heading:

• Glycan bioengineering in immunogen design for tumor T antigen immunotargeting. 30 Aug 2009
• Freeze-dry microscopy of protein/sugar mixtures: drying behavior, interpretation of collapse temperatures and a comparison to corresponding glass transition data. 30 Aug 2009
• Thermal denaturation of myoglobin in water--disaccharide matrixes: relation with the glass transition of the system. 18 Aug 2009
• Roles of mammalian structural units, ligand cluster and polyvalency in the Abrus precatorius agglutinin and glycoprotein recognition process. 17 Aug 2009
• Alterations of glycosaminoglycan disaccharide content and composition in colorectal cancer: structural and expressional studies. 30 Jul 2009
• The elucidation of the structure of Thermotoga maritima peptidoglycan reveals two novel types of cross-link. 17 Jun 2009
• An NMR investigation of putative interresidue H-bonding in methyl alpha-cellobioside in solution. 5 Jun 2009
• Chemoenzymatic synthesis of multivalent neoglycoconjugates carrying the helminth glycan antigen LDNF. 4 Jun 2009
• Quantification of heparan sulfate disaccharides using ion-pairing reversed-phase microflow high-performance liquid chromatography with electrospray ionization trap mass spectrometry. 30 May 2009
• Heat capacity changes in carbohydrates and protein-carbohydrate complexes. 11 May 2009
• Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein. 10 May 2009
• Molecular analysis of heparan sulfate biosynthetic enzyme machinery and characterization of heparan sulfate structure in Nematostella vectensis. 29 Apr 2009
• Ramachandran-type plots for glycosidic linkages: Examples from molecular dynamic simulations using the Glycam06 force field. 28 Apr 2009
• Toward fully synthetic homogeneous beta-human follicle-stimulating hormone (beta-hFSH) with a biantennary N-linked dodecasaccharide. synthesis of beta-hFSH with chitobiose units at the natural linkage sites. 27 Apr 2009
• Fractional Walden rule for electrolytes in supercooled disaccharide aqueous solutions. 21 Apr 2009
• Influence of the selected antioxidants on the stability of the Celsior solution used for perfusion and organ preservation purposes. 19 Apr 2009
• Size-tunable trehalose-based nanocavities: synthesis, structure, and inclusion properties of large-ring cyclotrehalans. 15 Apr 2009
• Using biological performance similarity to inform disaccharide library design. 13 Apr 2009
• Comparative solution and solid-phase glycosylations toward a disaccharide library. 8 Apr 2009
• Multivalent human blood group ABH and Lewis glycotopes are key recognition factors for a LFuc>Man binding lectin from phytopathogenic Ralstonia solanacearum. 30 Mar 2009

See a longer list of these articles.

Technical information about 'Disaccharides'

Definition: Oligosaccharides containing two monosaccharide units linked by a glycosidic bond.

Registry Number: 0

Descriptor UI: D004187

Alternative terms: Disaccharides;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D09.698.629.305;

Technical Notes: GEN; prefer specifics