Discrimination Learning - Drug effects
Research News and Information

Saturday, November 21, 2009

Spatial discrimination reversal learning in weanling rats is impaired by striatal administration of an NMDA-receptor antagonist.

25 Aug 2009 The striatum plays a major role in both motor control and learning and memory, including executive function and "behavioral flexibility." Lesion, temporary inactivation, and infusion of an N-methyl-d-aspartate (NMDA)-receptor antagonist into the ... Read more...

Dopaminergic modulation of olfactory bulb processing affects odor discrimination learning in rats.

30 Jul 2009 Olfactory behavioral studies have shown that, when modulated through systemic injections, D1 and D2 receptors have opposing effects on odor discrimination learning. In the present study, cannulated male Sprague-Dawley rats were used to investigate ... Read more...

Antagonism of the ethanol-like discriminative stimulus effects of ethanol, pentobarbital, and midazolam in cynomolgus monkeys reveals involvement of specific GABA(A) receptor subtypes.

27 Jul 2009 The gamma-aminobutyric acid (GABA)(A) receptors mediating the discriminative stimulus effects of ethanol were studied by comparing the potency of ethyl-8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazol(1,5-a)benzodiazepine-3-carboxylate (Ro15-4513) and ... Read more...

Latest indexed articles for 'Discrimination Learning - Drug effects'

These are the very latest articles for this heading:

• Spatial discrimination reversal learning in weanling rats is impaired by striatal administration of an NMDA-receptor antagonist. 25 Aug 2009
• Dopaminergic modulation of olfactory bulb processing affects odor discrimination learning in rats. 30 Jul 2009
• Antagonism of the ethanol-like discriminative stimulus effects of ethanol, pentobarbital, and midazolam in cynomolgus monkeys reveals involvement of specific GABA(A) receptor subtypes. 27 Jul 2009
• Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens. 27 Jul 2009
• Erythropoietin improves operant conditioning and stability of cognitive performance in mice. 6 Jul 2009
• Making context memories independent of the hippocampus. 22 Jun 2009
• Evidence of action sequence chunking in goal-directed instrumental conditioning and its dependence on the dorsomedial prefrontal cortex. 22 Jun 2009
• Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. 21 May 2009
• Rescue of Abeta(1-42)-induced memory impairment in day-old chick by facilitation of astrocytic oxidative metabolism: implications for Alzheimer's disease. 29 Apr 2009
• Preclinical evaluation of the abuse potential of the analgesic bicifadine. 6 Apr 2009
• Factors determining the effects of associative activation on habituation. 30 Mar 2009
• L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning. 17 Mar 2009
• Comparison of the discriminative stimulus effects of dimethyltryptamine with different classes of psychoactive compounds in rats. 12 Mar 2009
• Instrumental outcome devaluation with representation-mediated conditioning. 9 Mar 2009
• Discriminative stimulus effects of 3,4-methylenedioxymethamphetamine and its enantiomers in mice: pharmacokinetic considerations. 8 Mar 2009
• Ventral striatal dopamine modulation of different forms of behavioral flexibility. 2 Mar 2009
• Intrahippocampal administration of an NMDA-receptor antagonist impairs spatial discrimination reversal learning in weanling rats. 23 Feb 2009
• Carisoprodol-mediated modulation of GABAA receptors: in vitro and in vivo studies. 22 Feb 2009
• Interaction between nicotinic and dopaminergic therapies on cognition in a chronic Parkinson model. 5 Feb 2009
• A double dissociation between the effects of sub-pyrogenic systemic inflammation and hippocampal lesions on learning. 4 Feb 2009

See a longer list of these articles.

Technical information about 'Discrimination Learning'

Definition: Learning that is manifested in the ability to respond differentially to various stimuli.

Descriptor UI: D004193

Alternative terms: Discrimination Learning; Discrimination Learnings; Learning, Discrimination; Learnings, Discrimination;

Allowable Qualifiers: classification; drug effects; physiology; radiation effects; ethics;

Tree Number: F02.463.425.280;