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Disease Models, Animal
Research News and Information
Definition of 'Disease Models, Animal'Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases. Common names: Disease Models, Animal; Animal Disease Model; Animal Disease Models; Disease Model, Animal |
Saturday, November 21, 2009
Genetic complexity of absence seizures in substrains of C3H mice.
15 Dec 2009 
Absence epilepsy is a common form of idiopathic generalized epilepsy whose etiology is poorly understood because of genetic and phenotypic heterogeneity. The inbred mouse strain C3H/He exhibits spontaneous absence seizures characterized by spike and ... Read more...
Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes?
5 Dec 2009 Schizophrenia is a complex neuropsychiatric disorder whose etiology involves a mixture of genetic and environmental factors. By virtue of this complexity, schizophrenia is a field of research in which a number of key technologies converge: in ... Read more...
29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...
Latest indexed articles for 'Disease Models, Animal'
These are the very latest articles for this heading:
- Haplotype sharing excludes orthologous COL4A3, COL4A4 or MYH9 loci in hereditary nephritis in bull terriers.
28 Dec 2009 - Genetic complexity of absence seizures in substrains of C3H mice. 15 Dec 2009
- Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes? 5 Dec 2009
- Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
- Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model. 29 Nov 2009
- Overexpression of low-density lipoprotein receptor and lipid accumulation in intestinal polyps in Min mice. 29 Nov 2009
- Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine. 29 Nov 2009
- T cell-mediated control of Epstein-Barr virus infection in humanized mice. 13 Nov 2009
- The reduction of cell death and proliferation by p27(Kip1) minimizes DNA damage in an experimental model of genotoxicity. 13 Nov 2009
- Myelodysplastic syndromes. 3 Nov 2009
- Minocycline inhibition of photoreceptor degeneration. 30 Oct 2009
- Ovarian cancer update: lessons from morphology, molecules, and mice. 30 Oct 2009
- Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres. 30 Oct 2009
- Ex vivo [11C]-(+)-PHNO binding is unchanged in animal models displaying increased high-affinity states of the D2 receptor in vitro. 30 Oct 2009
- Redistribution of pulmonary blood flow impacts thermodilution-based extravascular lung water measurements in a model of acute lung injury. 30 Oct 2009
- Expanding treatment options for cocaine dependence. 30 Oct 2009
- S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo. 30 Oct 2009
- Angelman syndrome: current understanding and research prospects. 30 Oct 2009
- Mild hypothermia has no long-term impact on postischemic neurogenesis in rats. 30 Oct 2009
- Isoflurane preconditioning ameliorates endotoxin-induced acute lung injury and mortality in rats. 30 Oct 2009
See a longer list of these articles.
Technical information about 'Disease Models, Animal'
Definition: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Descriptor UI: D004195
Alternative terms: Disease Models, Animal; Animal Disease Model; Animal Disease Models; Disease Model, Animal;
Related Mesh Headings: Animals, Laboratory;
Tree Number: C22.232; E05.598.500; E05.599.395.080;
History Note: 70
Technical Notes: not a routine coordinate with experimental animal diseases: index only when the text indicates a disease model; when the model is the point of the article, coordinate IM with the specific disease (IM) + specific animal (IM) if pertinent