Disulfides
Research News and Information

Monday, November 23, 2009

Comprehensive secondary-structure analysis of disulfide variants of lysozyme by synchrotron-radiation vacuum-ultraviolet circular dichroism.

29 Sep 2009 To elucidate the effects of specific disulfide bridges (Cys6-Cys127, Cys30-Cys115, Cys64-Cys80, and Cys76-Cys94) on the secondary structure of hen lysozyme, the vacuum-ultraviolet circular dichroism (VUVCD) spectra of 13 species of ... Read more...

Drosophila glycoprotein 93 Is an ortholog of mammalian heat shock protein gp96 (grp94, HSP90b1, HSPC4) and retains disulfide bond-independent chaperone function for TLRs and integrins.

26 Sep 2009 Mammalian heat shock protein gp96 is an obligate chaperone for multiple integrins and TLRs, the mechanism of which is largely unknown. We have identified gp93 in Drosophila having high sequence homology to gp96. However, no functions were previously ... Read more...

Disulfide bond formation in yeast NAD+-specific isocitrate dehydrogenase.

20 Sep 2009 The tricarboxylic acid cycle NAD+-specific isocitrate dehydrogenase (IDH) of Saccharomyces cerevisiae is an octameric enzyme composed of four heterodimers of regulatory IDH1 and catalytic IDH2 subunits. Recent structural analyses revealed the close ... Read more...

Latest indexed articles for 'Disulfides'

These are the very latest articles for this heading:

• Comprehensive secondary-structure analysis of disulfide variants of lysozyme by synchrotron-radiation vacuum-ultraviolet circular dichroism. 29 Sep 2009
• Drosophila glycoprotein 93 Is an ortholog of mammalian heat shock protein gp96 (grp94, HSP90b1, HSPC4) and retains disulfide bond-independent chaperone function for TLRs and integrins. 26 Sep 2009
• Disulfide bond formation in yeast NAD+-specific isocitrate dehydrogenase. 20 Sep 2009
• Disulfide bridge regulates ligand-binding site selectivity in liver bile acid-binding proteins. 13 Sep 2009
• Structural characterization of the conformational change in calbindin-D28k upon calcium binding using differential surface modification analyzed by mass spectrometry. 13 Sep 2009
• Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX. 12 Sep 2009
• Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization. 12 Sep 2009
• A Kirkwood-Buff derived force field for thiols, sulfides, and disulfides. 8 Sep 2009
• The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu. 6 Sep 2009
• The folding pathway of onconase is directed by a conserved intermediate. 6 Sep 2009
• Morphology and molecular mobility of fibrous hard alpha-keratins by 1H, 13C, and 129Xe NMR. Sep 2009
• Methodology for determining disulfide linkage patterns of closely spaced cysteine residues. 30 Aug 2009
• Reducible disulfide-based non-viral gene delivery systems. 30 Aug 2009
• Reversibility and regioselectivity in thiol/disulfide interchange of tocinoic acid with glutathione in lyophilized solids. 30 Aug 2009
• Mass spectrometry study of PRL-3 phosphatase inactivation by disulfide bond formation and cysteine into glycine conversion. 30 Aug 2009
• Dissociation of disulfide-intact somatostatin ions: the roles of ion type and dissociation method. 30 Aug 2009
• Mutagenesis studies toward understanding allostery in thrombin. 30 Aug 2009
• Folding path and funnel scenarios for two small disulfide-bridged proteins. 30 Aug 2009
• Low-resolution structural studies of human Stanniocalcin-1. 25 Aug 2009
• Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence. 24 Aug 2009

See a longer list of these articles.

Technical information about 'Disulfides'

Definition: Chemical groups containing the covalent disulfide bonds -S-S-. The sulfur atoms can be bound to inorganic or organic moieties.

Registry Number: 0

Descriptor UI: D004220

Alternative terms: Disulfides;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D01.248.497.158.874.390; D01.875.350.850.150; D02.886.520.150;

History Note: 73(71)