Diynes - Chemistry
Research News and Information

Sunday, November 22, 2009

Nickel-catalyzed oxidative coupling reactions of two different terminal alkynes using O(2) as the oxidant at room temperature: facile syntheses of unsymmetric 1,3-diynes.

3 Feb 2009 Two different terminal alkynes now can be coupled together in the presence of NiCl(2).6H(2)O/CuI by using an excess of one of the terminal alkyne substrates. The new method employed 20 mol % TMEDA as the ligand and environmentally benign O(2) or air ... Read more...

Highly efficient access to bi- and tricyclic ketals through gold-catalyzed tandem reactions of 4-acyl-1,6-diynes.

30 Dec 2008 Single step: Fused bicyclic and bridged tricyclic ketals were synthesized in a single step from the reactions of easily available 4-acyl-1,6-diynes with H(2)O and alkanols (see scheme). The highly efficient AuCl(3)-catalyzed multicomponent domino ... Read more...

Biomass and content of ginsenosides and polyacetylenes in American ginseng roots can be increased without affecting the profile of bioactive compounds.

14 Dec 2008 Fifty selected roots from a 7-year-old American ginseng (Panax quinquefolium L.) plant population grown in Denmark, with root weights varying from 191 to 490 g fresh weight (FW), were investigated for bioactive ginsenosides and polyacetylenes (PAs) ... Read more...

Latest indexed articles for 'Diynes - Chemistry'

These are the very latest articles for this heading:

• Heterogeneously catalyzed efficient alkyne-alkyne homocoupling by supported copper hydroxide on titanium oxide. Aug 2009
• Nickel-catalyzed oxidative coupling reactions of two different terminal alkynes using O(2) as the oxidant at room temperature: facile syntheses of unsymmetric 1,3-diynes. 3 Feb 2009
• From conjugated tertiary skipped diynes to chain-functionalized tetrasubstituted pyrroles. 30 Dec 2008
• Highly efficient access to bi- and tricyclic ketals through gold-catalyzed tandem reactions of 4-acyl-1,6-diynes. 30 Dec 2008
• Biomass and content of ginsenosides and polyacetylenes in American ginseng roots can be increased without affecting the profile of bioactive compounds. 14 Dec 2008
• Indoleacetic acid falcarindiol ester induces granulocytic differentiation of the human leukemia cell line HL-60. 22 Nov 2008
• Synthesis of 2-cyclohexenone derivatives via gold(I)-catalyzed hydrative cyclization of 1,6-diynes. 26 Aug 2008
• Antimycobacterial polyacetylenes from Levisticum officinale. 29 Apr 2008
• Substituent effects in the preparation of naphthacenes by the coupling reaction of diyne-derived zirconacyclopentadienes with tetraiodobenzene. 30 Jan 2008
• Novel coumarin glycoside and phenethyl vanillate from Notopterygium forbesii and their binding affinities for opioid and dopamine receptors. 29 Dec 2007
• Antiproliferative effect of panaxynol on RASMCs via inhibition of ERK1/2 and CREB. 6 Dec 2007
• Nickel(0)-catalyzed [2 + 2 + 2 + 2] cycloadditions of terminal diynes for the synthesis of substituted cyclooctatetraenes. 9 Oct 2007
• Synthesis and unusual reactivity of N-tosyl-4,5-benzoazacyclodeca-2,6-diyne, yneamino-containing enediyne. 16 Sep 2007
• Metal-free access to fully substituted skipped diynes. An efficient chemodifferentiating A2BB' 4CR manifold. 7 Jun 2007
• Triggering of the Bergman cyclization by photochemical ring contraction. Facile cycloaromatization of benzannulated cyclodeca-3,7-diene-1,5-diynes. 11 Mar 2007
• CuCl-induced formation and migration of isoindazolyl carbenoids. 4 Mar 2007
• A crossed molecular beam study on the formation of hexenediynyl radicals (H(2)CCCCCCH; C(6)H(3) (X(2)A')) via reactions of tricarbon molecules, C(3)(X(1)Sigma(g)(+)), with allene (H(2)CCCH(2); X(1)A(1)) and methylacetylene (CH(3)CCH; X(1)A(1)). 13 Feb 2007
• Alpha-hydroxy esters via enantioselective hydrogen-mediated C-C coupling: regiocontrolled reactions of silyl-substituted 1,3-diynes. 15 Aug 2006
• Synthesis of spirocyclic C-arylribosides via cyclotrimerization. Aug 2006
• An in situ approach for nickel-catalyzed cycloaddition. 19 Jul 2006

See a longer list of these articles.

Technical information about 'Diynes'

Definition: Compounds with two triple bonds. Some of them are CYTOTOXINS.

Registry Number: 0

Descriptor UI: D053280

Alternative terms: Diynes;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.455.326.397.662.500;

History Note: 2007