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DNA - Genetics
Research News and Information
Definition of 'DNA'A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine). |
Saturday, November 21, 2009
30 Oct 2009 
OBJECTIVE: To report a 3-generation white family clinically diagnosed variably with Wagner, Stickler, and Jansen syndromes and screened for sequence variants in the COL2A1 and CSPG2 genes. Wagner syndrome is an autosomal dominant vitreoretinopathy ... Read more...
30 Oct 2009 We assessed the structure and latitudinal selection that might result in sensitivities to critical day-lengths that trigger diapause between Culex pipiens populations distributed along North-South and East-West axes in eastern North America. Strong ... Read more...
Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies.
30 Oct 2009 Epigenetic mechanisms such as DNA methylation and modifications to histone proteins regulate high-order DNA structure and gene expression. Aberrant epigenetic mechanisms are involved in the development of many diseases, including cancer. The ... Read more...
Latest indexed articles for 'DNA - Genetics'
These are the very latest articles for this heading:
- Mutational hot spot potential of a novel base pair mutation of the CSPG2 gene in a family with Wagner syndrome. 30 Oct 2009
- Effects of latitude and longitude on the population structure of Culex pipiens s.l., vectors of West Nile virus in North America. 30 Oct 2009
- Tip60-ing the balance in DSB repair.
30 Oct 2009 - Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. 30 Oct 2009
- Biased segregation of DNA and centrosomes: moving together or drifting apart? 30 Oct 2009
- Epigenetic regulation of Myc on retinoic acid receptor beta and PDLIM4 in RWPE1 cells. 30 Oct 2009
- Microdissection and chromosome painting of X and B chromosomes in the grasshopper Eyprepocnemis plorans. 25 Oct 2009
- Characterisation of a GC-rich telomeric satellite DNA in Eumeces schneideri Daudin (Reptilia, Scincidae). 25 Oct 2009
- Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers. 12 Oct 2009
- Heretical DNA sequences? 7 Oct 2009
- Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. 6 Oct 2009
- Gene copy number: learning to count past two. 29 Sep 2009
- Reply to: "Experimental aspects of copy number variant assays at CCL3L1". 29 Sep 2009
- Experimental aspects of copy number variant assays at CCL3L1. 29 Sep 2009
- A RYR1 mutation associated with recessive congenital myopathy and dominant malignant hyperthermia in Asian families. 29 Sep 2009
- Implication of sex and SORL1 variants in italian patients with Alzheimer disease. 29 Sep 2009
- Insertion/deletion polymorphism in alpha2-adrenergic receptor gene is a genetic risk factor for sudden cardiac death. 29 Sep 2009
- Cardiac amyloidosis in African Americans: comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis. 29 Sep 2009
- Metal ion interactions in the DNA cleavage/ligation active site of human topoisomerase IIalpha. 27 Sep 2009
- Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor. 26 Sep 2009
See a longer list of these articles.
Technical information about 'DNA'
Definition: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Chemical name: Deoxyribonucleic acids
Registry Number: 9007-49-2
Descriptor UI: D004247
Alternative terms: DNA; Deoxyribonucleic Acid; DNA, B-Form; B-Form DNA; DNA, B Form; B-DNA; DNA, Double-Stranded; DNA, Double Stranded; Double-Stranded DNA; ds-DNA;
Related Mesh Headings: Genetic Code; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid; DNA Primers;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D13.444.308;
Technical Notes: GEN: prefer specifics; /biosyn permitted but consider also DNA REPLICATION; structural DNA models = DNA (IM) + MOLECULAR MODELS (IM)