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DNA - Isolation & purification
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Definition of 'DNA'

A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).

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Sunday, November 22, 2009

Citrulline as a marker for chemotherapy induced mucosal barrier injury in pediatric patients.

13 Dec 2009 BACKGROUND: The currently used National Cancer Institute (NCI) adverse events criteria for mucosal barrier injury (MBI) are insufficient for use in children. We searched for objective, easily measurable indicators for MBI in children with cancer. ... Read more...


Effect of adipose tissue on the sexual dimorphism in metabolic flexibility.

30 Oct 2009 Metabolic flexibility is the ability to transition between fat oxidation (fasting state) and glucose oxidation (fed state). We hypothesized that adipose tissue inflammation and lipid metabolism contribute to sexual dimorphism in metabolic ... Read more...


Characterisation of a GC-rich telomeric satellite DNA in Eumeces schneideri Daudin (Reptilia, Scincidae).

25 Oct 2009 A hitherto undescribed satellite DNA family (AvaII satDNA) has been isolated and characterised in Eumeces schneideri, a squamate reptile belonging to the family Scincidae. AvaII satDNA is characterised by a monomer length of 208 bp, a GC content of ... Read more...

 

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Technical information about 'DNA'

Definition: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).

Chemical name: Deoxyribonucleic acids

Registry Number: 9007-49-2

Descriptor UI: D004247

Alternative terms: DNA; Deoxyribonucleic Acid; DNA, B-Form; B-Form DNA; DNA, B Form; B-DNA; DNA, Double-Stranded; DNA, Double Stranded; Double-Stranded DNA; ds-DNA;

Related Mesh Headings: Genetic Code; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid; DNA Primers;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D13.444.308;

Technical Notes: GEN: prefer specifics; /biosyn permitted but consider also DNA REPLICATION; structural DNA models = DNA (IM) + MOLECULAR MODELS (IM)

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