DNA-Binding Proteins - Genetics
Research News and Information

Monday, November 23, 2009

Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2.

29 Nov 2009 The nuclear protein methyl-transferase Retinoblastoma-interacting zinc-finger protein 1 (RIZ1) is considered to be a downstream effector of estrogen action in target tissues. Silencing of RIZ1 expression is common in many tumors. We analyzed RIZ1 ... Read more...

p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck.

29 Nov 2009 P73 plays an important role in modulating cell-cycle control, inducing apoptosis, and inhibiting cell growth. A novel noncoding p73 G4C14-to-A4T14 exon 2 polymorphism was associated with risk of squamous cell carcinoma of the head and neck (SCCHN). ... Read more...

Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma.

13 Nov 2009 Barrett's esophagus (BE) is a metaplastic condition caused by chronic gastroesophageal reflux which represents an early step in the development of esophageal adenocarcinoma (EAC). Single-nucleotide polymorphism microarray (SNP-chip) analysis is a ... Read more...

Latest indexed articles for 'DNA-Binding Proteins - Genetics'

These are the very latest articles for this heading:

• Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2. 29 Nov 2009
• p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck. 29 Nov 2009
• Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma. 13 Nov 2009
• The mechanisms underlying MMR deficiency in immunodeficiency-related non-Hodgkin lymphomas are different from those in other sporadic microsatellite instable neoplasms. 13 Nov 2009
• The heritability and genetics of frontotemporal lobar degeneration. Nov 2009
• Carcinoma of the breast with medullary-like features: diagnostic challenges and relationship with BRCA1 and EZH2 functions. 30 Oct 2009
• MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer. 30 Oct 2009
• Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel. 30 Oct 2009
• The impacts of ERCC1 gene exon VIII alternative splicing on cisplatin-resistance in ovarian cancer cells. 30 Oct 2009
• Epigenetic regulation of Myc on retinoic acid receptor beta and PDLIM4 in RWPE1 cells. 30 Oct 2009
• Oncogenic human papillomaviruses block expression of the B-cell translocation gene-2 tumor suppressor gene. 30 Oct 2009
• Risk of pancreatic cancer in families with Lynch syndrome. 26 Oct 2009
• Replication-deficient rabies virus-based vaccines are safe and immunogenic in mice and nonhuman primates. 13 Oct 2009
• Impact of nonnatural amino acid mutagenesis on the in vivo function and binding modes of a transcriptional activator. 12 Oct 2009
• Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice. 10 Oct 2009
• A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates. 6 Oct 2009
• IL-7 is essential for lymphopenia-driven turnover of colitogenic CD4(+) memory T cells in chronic colitis. 29 Sep 2009
• Meis cofactors control HDAC and CBP accessibility at Hox-regulated promoters during zebrafish embryogenesis. 29 Sep 2009
• Identifying the molecular signature of the interstitial deletion 7q subgroup of uterine leiomyomata using a paired analysis. 29 Sep 2009
• XRCC1 codon 280 and ERCC2 codon 751 polymorphisms and risk of esophageal squamous cell carcinoma in a Chinese population. 29 Sep 2009

See a longer list of these articles.

Technical information about 'DNA-Binding Proteins'

Definition: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.

Registry Number: 0

Descriptor UI: D004268

Alternative terms: DNA-Binding Proteins; DNA Binding Proteins; DNA Binding Protein; Binding Protein, DNA; Single-Stranded DNA Binding Proteins; Single Stranded DNA Binding Proteins; SS DNA BP; DNA Single-Stranded Binding Protein; DNA Single Stranded Binding Protein; Single-Stranded DNA-Binding Protein; DNA-Binding Protein, Single-Stranded; Single Stranded DNA Binding Protein; DNA Helix Destabilizing Proteins;

Related Mesh Headings: DNA Replication; Zinc Fingers; Leucine Zippers; Helix-Loop-Helix Motifs; Helix-Turn-Helix Motifs;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260;

Online Note: use DNA UNWINDING PROTEINS to search DNA HELIX DESTABILIZING PROTEINS 1980-83

History Note: 84; DNA HELIX DESTABILIZING PROTEINS was see DNA UNWINDING PROTEINS 1980-83