DNA-Binding Proteins
Research News and Information

Sunday, November 22, 2009

Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2.

29 Nov 2009 The nuclear protein methyl-transferase Retinoblastoma-interacting zinc-finger protein 1 (RIZ1) is considered to be a downstream effector of estrogen action in target tissues. Silencing of RIZ1 expression is common in many tumors. We analyzed RIZ1 ... Read more...

p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck.

29 Nov 2009 P73 plays an important role in modulating cell-cycle control, inducing apoptosis, and inhibiting cell growth. A novel noncoding p73 G4C14-to-A4T14 exon 2 polymorphism was associated with risk of squamous cell carcinoma of the head and neck (SCCHN). ... Read more...

Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation.

13 Nov 2009 New treatment approaches are needed for hormone refractory prostate cancer. Oncolytic adenoviruses are promising anti-cancer agents, and their efficacy can be improved by combining with conventional therapies such as ionizing radiation. The aim of ... Read more...

Latest indexed articles for 'DNA-Binding Proteins'

These are the very latest articles for this heading:

• Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2. 29 Nov 2009
• p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck. 29 Nov 2009
• Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation. 13 Nov 2009
• Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma. 13 Nov 2009
• The mechanisms underlying MMR deficiency in immunodeficiency-related non-Hodgkin lymphomas are different from those in other sporadic microsatellite instable neoplasms. 13 Nov 2009
• The periplasmic chaperone Skp facilitates targeting, insertion, and folding of OmpA into lipid membranes with a negative membrane surface potential. Nov 2009
• The heritability and genetics of frontotemporal lobar degeneration. Nov 2009
• Carcinoma of the breast with medullary-like features: diagnostic challenges and relationship with BRCA1 and EZH2 functions. 30 Oct 2009
• 5,6-Dihydrothymine impairs the base excision repair pathway of a closely opposed AP site or single-strand break. 30 Oct 2009
• MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer. 30 Oct 2009
• Cellular dichotomy between anchorage-independent growth responses to bFGF and TPA reflects molecular switch in commitment to carcinogenesis. 30 Oct 2009
• Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel. 30 Oct 2009
• Detailed cytogenetic and array analysis of pediatric primitive sarcomas reveals a recurrent CIC-DUX4 fusion gene event. 30 Oct 2009
• The impacts of ERCC1 gene exon VIII alternative splicing on cisplatin-resistance in ovarian cancer cells. 30 Oct 2009
• Epigenetic regulation of Myc on retinoic acid receptor beta and PDLIM4 in RWPE1 cells. 30 Oct 2009
• Oncogenic human papillomaviruses block expression of the B-cell translocation gene-2 tumor suppressor gene. 30 Oct 2009
• Risk of pancreatic cancer in families with Lynch syndrome. 26 Oct 2009
• The differential role of motor cortex in stretch reflex modulation induced by changes in environmental mechanics and verbal instruction. 19 Oct 2009
• Functionally mature CD4 and CD8 TCRalphabeta cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells. 13 Oct 2009
• Replication-deficient rabies virus-based vaccines are safe and immunogenic in mice and nonhuman primates. 13 Oct 2009

See a longer list of these articles.

Technical information about 'DNA-Binding Proteins'

Definition: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.

Registry Number: 0

Descriptor UI: D004268

Alternative terms: DNA-Binding Proteins; DNA Binding Proteins; DNA Binding Protein; Binding Protein, DNA; Single-Stranded DNA Binding Proteins; Single Stranded DNA Binding Proteins; SS DNA BP; DNA Single-Stranded Binding Protein; DNA Single Stranded Binding Protein; Single-Stranded DNA-Binding Protein; DNA-Binding Protein, Single-Stranded; Single Stranded DNA Binding Protein; DNA Helix Destabilizing Proteins;

Related Mesh Headings: DNA Replication; Zinc Fingers; Leucine Zippers; Helix-Loop-Helix Motifs; Helix-Turn-Helix Motifs;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260;

Online Note: use DNA UNWINDING PROTEINS to search DNA HELIX DESTABILIZING PROTEINS 1980-83

History Note: 84; DNA HELIX DESTABILIZING PROTEINS was see DNA UNWINDING PROTEINS 1980-83