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DNA, Mitochondrial - Isolation & purification
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Definition of 'DNA, Mitochondrial'

Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial GENOME is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins.

Common names: DNA, Mitochondrial; mtDNA; Mitochondrial DNA

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Saturday, November 21, 2009

Primer extension capture: targeted sequence retrieval from heavily degraded DNA sources.

Sep 2009 We present a method of targeted DNA sequence retrieval from DNA sources which are heavily degraded and contaminated with microbial DNA, as is typical of ancient bones. The method greatly reduces sample destruction and sequencing demands relative to ... Read more...


Targeted retrieval and analysis of five Neandertal mtDNA genomes.

15 Jul 2009 Analysis of Neandertal DNA holds great potential for investigating the population history of this group of hominins, but progress has been limited due to the rarity of samples and damaged state of the DNA. We present a method of targeted ancient DNA ... Read more...


Perfluorooctanoic acid stimulated mitochondrial biogenesis and gene transcription in rats.

14 Jul 2009 Perfluorooctanoic acid (PFOA), used in the production of non-stick surface compounds, exhibits a worldwide distribution in the serum of humans and wildlife. In rodents PFOA transactivates PPARalpha and PPARgamma nuclear receptors and increases ... Read more...

 

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Technical information about 'DNA, Mitochondrial'

Definition: Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial GENOME is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins.

Registry Number: 0

Descriptor UI: D004272

Alternative terms: DNA, Mitochondrial; mtDNA; Mitochondrial DNA;

Related Mesh Headings: Genes, Mitochondrial;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D13.444.308.283.225;

History Note: 74(73)

Technical Notes: IM; /drug eff /ultrastruct permitted; DF: note short X ref

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