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DNA
Research News and Information
Definition of 'DNA'A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine). |
Saturday, November 21, 2009
Citrulline as a marker for chemotherapy induced mucosal barrier injury in pediatric patients.
13 Dec 2009 
BACKGROUND: The currently used National Cancer Institute (NCI) adverse events criteria for mucosal barrier injury (MBI) are insufficient for use in children. We searched for objective, easily measurable indicators for MBI in children with cancer. ... Read more...
Characterization of covalent adducts of nucleosides and DNA formed by reaction with levuglandin.
15 Nov 2009 Enhanced expression of cyclooxygenase-2 (COX-2) is associated with development of several cancers. The product of COX-2, prostaglandin H(2) (PGH(2)), can undergo spontaneous rearrangement and nonenzymatic ring cleavage to form the highly reactive ... Read more...
8 Nov 2009 The study of interactions of protein with DNA is important for gaining a fundamental understanding of how numerous biological processes occur, including recombination, transcription, repair, etc. In this study, we use the EcoRII restriction enzyme, ... Read more...
Latest indexed articles for 'DNA'
These are the very latest articles for this heading:
- Biomarkers for mucositis assessment.
13 Dec 2009 - Citrulline as a marker for chemotherapy induced mucosal barrier injury in pediatric patients. 13 Dec 2009
- Characterization of covalent adducts of nucleosides and DNA formed by reaction with levuglandin. 15 Nov 2009
- Single-molecule dynamics of the DNA-EcoRII protein complexes revealed with high-speed atomic force microscopy. 8 Nov 2009
- Characterization and structure of the manganese-responsive transcriptional regulator ScaR. Nov 2009
- Herpes simplex virus-1 helicase-primase: roles of each subunit in DNA binding and phosphodiester bond formation. Nov 2009
- Mutational hot spot potential of a novel base pair mutation of the CSPG2 gene in a family with Wagner syndrome. 30 Oct 2009
- Effects of latitude and longitude on the population structure of Culex pipiens s.l., vectors of West Nile virus in North America. 30 Oct 2009
- Tip60-ing the balance in DSB repair. 30 Oct 2009
- Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. 30 Oct 2009
- Effect of adipose tissue on the sexual dimorphism in metabolic flexibility. 30 Oct 2009
- Biased segregation of DNA and centrosomes: moving together or drifting apart? 30 Oct 2009
- Diagnostic accuracy of neutrophil-derived circulating free DNA (cf-DNA/NETs) for septic arthritis. 30 Oct 2009
- Epigenetic regulation of Myc on retinoic acid receptor beta and PDLIM4 in RWPE1 cells. 30 Oct 2009
- E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin. 30 Oct 2009
- E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells. 30 Oct 2009
- Microdissection and chromosome painting of X and B chromosomes in the grasshopper Eyprepocnemis plorans. 25 Oct 2009
- Characterisation of a GC-rich telomeric satellite DNA in Eumeces schneideri Daudin (Reptilia, Scincidae). 25 Oct 2009
- The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA. 18 Oct 2009
- Chondrogenesis on BMP-6 loaded chitosan scaffolds in stationary and dynamic cultures. 13 Oct 2009
See a longer list of these articles.
Technical information about 'DNA'
Definition: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Chemical name: Deoxyribonucleic acids
Registry Number: 9007-49-2
Descriptor UI: D004247
Alternative terms: DNA; Deoxyribonucleic Acid; DNA, B-Form; B-Form DNA; DNA, B Form; B-DNA; DNA, Double-Stranded; DNA, Double Stranded; Double-Stranded DNA; ds-DNA;
Related Mesh Headings: Genetic Code; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid; DNA Primers;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D13.444.308;
Technical Notes: GEN: prefer specifics; /biosyn permitted but consider also DNA REPLICATION; structural DNA models = DNA (IM) + MOLECULAR MODELS (IM)