Dopamine - Metabolism
Research News and Information

Saturday, November 21, 2009

GPR37 surface expression enhancement via N-terminal truncation or protein-protein interactions.

Nov 2009 GPR37, also known as the parkin-associated endothelin-like receptor (Pael-R), is an orphan G-protein-coupled receptor (GPCR) that exhibits poor plasma membrane expression when expressed in most cell types. We sought to find ways to enhance GPR37 ... Read more...

Differential corticosteroid receptor regulation of mesoaccumbens dopamine efflux during the peak and nadir of the circadian rhythm: a molecular equilibrium in the midbrain?

30 Oct 2009 Corticosteroid receptor modulation of mesoaccumbens dopamine neurotransmission is believed to be a key neurobiological mechanism mediating the effects of stress in addiction. Importantly, nucleus accumbens (NAc) subregions (core and shell) are ... Read more...

Endocannabinoid modulation of amphetamine sensitization is disrupted in a rodent model of lesion-induced dopamine dysregulation.

30 Oct 2009 We tested the hypothesis that increased dopaminergic sensitivity induced by olfactory bulbectomy is mediated by dysregulation of endocannabinoid signaling. Bilateral olfactory bulbectomy induces behavioral and neurobiological symptomatology related ... Read more...

Latest indexed articles for 'Dopamine - Metabolism'

These are the very latest articles for this heading:

• GPR37 surface expression enhancement via N-terminal truncation or protein-protein interactions. Nov 2009
• Differential corticosteroid receptor regulation of mesoaccumbens dopamine efflux during the peak and nadir of the circadian rhythm: a molecular equilibrium in the midbrain? 30 Oct 2009
• Endocannabinoid modulation of amphetamine sensitization is disrupted in a rodent model of lesion-induced dopamine dysregulation. 30 Oct 2009
• The time course of dopamine transmission in the ventral tegmental area. 19 Oct 2009
• SnapShot: pathogenesis of Parkinson's disease. 14 Oct 2009
• Writing memories with light-addressable reinforcement circuitry. 14 Oct 2009
• Neuroscience. Fetal cells again? 14 Oct 2009
• Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription. 5 Oct 2009
• Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting. 5 Oct 2009
• A neurocomputational model for cocaine addiction. 29 Sep 2009
• The dopaminergic stabilizer ASP2314/ACR16 selectively interacts with D2(High) receptors. 29 Sep 2009
• Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells. 29 Sep 2009
• Wireless Instantaneous Neurotransmitter Concentration System-based amperometric detection of dopamine, adenosine, and glutamate for intraoperative neurochemical monitoring. 29 Sep 2009
• Development of the Wireless Instantaneous Neurotransmitter Concentration System for intraoperative neurochemical monitoring using fast-scan cyclic voltammetry. 29 Sep 2009
• Transcriptomic and proteomic analyses of seasonal photoperiodism in the pea aphid. 27 Sep 2009
• Glutamate controls growth rate and branching of dopaminergic axons. 21 Sep 2009
• The dopaminergic system of the telencephalo-diencephalic areas of the vertebrate brain in the organization of the sleep-waking cycle. 21 Sep 2009
• Intrarenal dopamine attenuates deoxycorticosterone acetate/high salt-induced blood pressure elevation in part through activation of a medullary cyclooxygenase 2 pathway. 19 Sep 2009
• Neuroprotective effect of L-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson's disease: a direct comparison study. 14 Sep 2009
• Dopamine modulation of the in vivo acetylcholine response in the Drosophila mushroom body. 13 Sep 2009

See a longer list of these articles.

Technical information about 'Dopamine'

Definition: One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.

Chemical name: 1,2-Benzenediol, 4-(2-aminoethyl)-

Registry Number: 51-61-6

Descriptor UI: D004298

Alternative terms: Dopamine; Hydroxytyramine; 3,4-Dihydroxyphenethylamine; 3,4 Dihydroxyphenethylamine; 4-(2-Aminoethyl)-1,2-benzenediol; Intropin; Dopamine Hydrochloride; Hydrochloride, Dopamine;

Related Mesh Headings: Levodopa; Receptors, Dopamine; Dopamine Agents;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Pharmacological Action: Sympathomimetics; Dopamine Agents; Cardiotonic Agents;

Tree Number: D02.092.211.215.311.342; D02.092.311.342;