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Dopamine - Pharmacology
Research News and Information
Definition of 'Dopamine'One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action. Common names: Dopamine; Hydroxytyramine; 3,4-Dihydroxyphenethylamine; 3,4 Dihydroxyphenethylamine; 4-(2-Aminoethyl)-1,2-benzenediol; Intropin; Dopamine Hydrochloride; Hydrochloride, Dopamine |
Monday, November 23, 2009
The time course of dopamine transmission in the ventral tegmental area.
19 Oct 2009 
Synaptic transmission mediated by G-protein coupled receptors (GPCR) is not generally thought to be point-to-point. To determine the extent over which dopamine signals in the midbrain, the present study examined the concentration and time course of ... Read more...
The dopaminergic stabilizer ASP2314/ACR16 selectively interacts with D2(High) receptors.
29 Sep 2009 Dopaminergic stabilizers are recognized as compounds that can either enhance or antagonize dopamine (DA)-dependent behaviors depending on the prevailing dopaminergic tone. The dopaminergic stabilizer ASP2314 is being tested clinically and has been ... Read more...
Activity of Hb9 interneurons during fictive locomotion in mouse spinal cord.
14 Sep 2009 Hb9 interneurons (Hb9 INs) are putative components of the mouse spinal locomotor central pattern generator (CPG) and candidates for the rhythm-generating kernel. Studies in slices and hemisected spinal cords showed that Hb9 INs display TTX-resistant ... Read more...
Latest indexed articles for 'Dopamine - Pharmacology'
These are the very latest articles for this heading:
- The time course of dopamine transmission in the ventral tegmental area. 19 Oct 2009
- The dopaminergic stabilizer ASP2314/ACR16 selectively interacts with D2(High) receptors. 29 Sep 2009
- Activity of Hb9 interneurons during fictive locomotion in mouse spinal cord. 14 Sep 2009
- Dopamine modulation of the in vivo acetylcholine response in the Drosophila mushroom body. 13 Sep 2009
- Effects of donor pretreatment with dopamine on graft function after kidney transplantation: a randomized controlled trial. 7 Sep 2009
- Distribution of D1 and D5 dopamine receptors in the primate and rat basolateral amygdala. 6 Aug 2009
- Nucleus accumbens neurons exhibit synaptic scaling that is occluded by repeated dopamine pre-exposure. 5 Aug 2009
- The long-term survival rate of catecholamine-resistant septic shock in Japanese patients who received vasopressin therapy. 30 Jul 2009
- Dopamine D2High receptors stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil. 30 Jul 2009
- Hemodynamic effects of dobutamine and dopexamine after cardiopulmonary bypass in pediatric cardiac surgery. 22 Jul 2009
- Identification and characterization of a novel amphioxus dopamine D-like receptor. 21 Jul 2009
- Gain in sensitivity and loss in temporal contrast of STDP by dopaminergic modulation at hippocampal synapses. 18 Jul 2009
- Decreased ventilatory response to exercise by dopamine-induced inhibition of peripheral chemosensitivity. 16 Jul 2009
- Differential dopaminergic modulation of neostriatal synaptic connections of striatopallidal axon collaterals. 13 Jul 2009
- Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. 29 Jun 2009
- Arrestin3 mediates D(2) dopamine receptor internalization.
29 Jun 2009 - Bilobalide modulates serotonin-controlled behaviors in the nematode Caenorhabditis elegans.
20 Jun 2009 - A new method to study sensory modulation of locomotor networks by activation of thermosensitive cutaneous afferents using a hindlimb attached spinal cord preparation. 16 Jun 2009
- N-arachidonyl dopamine sensitizes rat capsaicin-sensitive lung vagal afferents via activation of TRPV1 receptors. 15 Jun 2009
- Characteristics of the functioning of the hippocampal formation in waking and paradoxical sleep. 9 Jun 2009
See a longer list of these articles.
Technical information about 'Dopamine'
Definition: One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
Chemical name: 1,2-Benzenediol, 4-(2-aminoethyl)-
Registry Number: 51-61-6
Descriptor UI: D004298
Alternative terms: Dopamine; Hydroxytyramine; 3,4-Dihydroxyphenethylamine; 3,4 Dihydroxyphenethylamine; 4-(2-Aminoethyl)-1,2-benzenediol; Intropin; Dopamine Hydrochloride; Hydrochloride, Dopamine;
Related Mesh Headings: Levodopa; Receptors, Dopamine; Dopamine Agents;
Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;
Pharmacological Action: Sympathomimetics; Dopamine Agents; Cardiotonic Agents;
Tree Number: D02.092.211.215.311.342; D02.092.311.342;