Dopamine - Secretion
Research News and Information

Saturday, November 21, 2009

In vivo measurement of somatodendritic release of dopamine in the ventral tegmental area.

30 Oct 2009 The ventral tegmental area (VTA), the locus of mesolimbic dopamine cell bodies, contains dopamine. Experiments in brain slices have demonstrated that VTA dopamine can be released by local electrical stimulation. Measurements with both push-pull ... Read more...

Chronic nicotine selectively enhances alpha4beta2* nicotinic acetylcholine receptors in the nigrostriatal dopamine pathway.

5 Oct 2009 These electrophysiological experiments, in slices and intact animals, study the effects of in vivo chronic exposure to nicotine on functional alpha4beta2* nAChRs in the nigrostriatal dopaminergic (DA) pathway. Recordings were made in wild-type and ... Read more...

Neural encoding of cocaine-seeking behavior is coincident with phasic dopamine release in the accumbens core and shell.

2 Sep 2009 Mesolimbic dopamine neurons projecting from the ventral tegmental area to the nucleus accumbens (NAc) are part of a complex circuit mediating cocaine-directed behaviors. However, the precise role of rapid (subsecond) dopamine release within the ... Read more...

Latest indexed articles for 'Dopamine - Secretion'

These are the very latest articles for this heading:

• In vivo measurement of somatodendritic release of dopamine in the ventral tegmental area. 30 Oct 2009
• Chronic nicotine selectively enhances alpha4beta2* nicotinic acetylcholine receptors in the nigrostriatal dopamine pathway. 5 Oct 2009
• Neural encoding of cocaine-seeking behavior is coincident with phasic dopamine release in the accumbens core and shell. 2 Sep 2009
• Antidepressant treatment facilitates dopamine release and drug seeking behavior in a genetic animal model of depression. 13 Jul 2009
• Tonic autoinhibition contributes to the heterogeneity of evoked dopamine release in the rat striatum. 12 Jul 2009
• [Role of Cdk5 in dopamine signaling and addiction] 30 May 2009
• Impaired dopamine release and synaptic plasticity in the striatum of parkin-/- mice. 3 May 2009
• Intrahippocampal infusions of anisomycin produce amnesia: contribution of increased release of norepinephrine, dopamine, and acetylcholine. 27 Apr 2009
• Dopamine release in dissociable striatal subregions predicts the different effects of oral methylphenidate on reversal learning and spatial working memory. 13 Apr 2009
• Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study. Apr 2009
• [Glucose metabolism in the basal ganglia] 30 Mar 2009
• Measurement of plasmalemmal dopamine transport, vesicular dopamine transport, and K(+)-stimulated dopamine release in frozen rat brain tissue. 26 Mar 2009
• Single administration of 1-benzyl-1,2,3,4-tetrahydroisoquinoline increases the extracellular concentration of dopamine in rat striatum. 10 Mar 2009
• Local salsolinol modulates dopamine extracellular levels from rat nucleus accumbens: shell/core differences. 3 Mar 2009
• Quantitative evaluation of serotonin release and clearance in Drosophila. 2 Mar 2009
• Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release. 22 Feb 2009
• Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking. 20 Feb 2009
• Enhancing effects of morphine on methamphetamine-induced reinforcing behavior and its association with dopamine release and metabolism in mice. 18 Feb 2009
• Lateralized sex differences in stress-induced dopamine release in the rat. 16 Feb 2009
• Effects of TRK-820, a selective kappa opioid receptor agonist, on rat schizophrenia models. 3 Feb 2009

See a longer list of these articles.

Technical information about 'Dopamine'

Definition: One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.

Chemical name: 1,2-Benzenediol, 4-(2-aminoethyl)-

Registry Number: 51-61-6

Descriptor UI: D004298

Alternative terms: Dopamine; Hydroxytyramine; 3,4-Dihydroxyphenethylamine; 3,4 Dihydroxyphenethylamine; 4-(2-Aminoethyl)-1,2-benzenediol; Intropin; Dopamine Hydrochloride; Hydrochloride, Dopamine;

Related Mesh Headings: Levodopa; Receptors, Dopamine; Dopamine Agents;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Pharmacological Action: Sympathomimetics; Dopamine Agents; Cardiotonic Agents;

Tree Number: D02.092.211.215.311.342; D02.092.311.342;