Dopamine Uptake Inhibitors - Administration & dosage
Research News and Information

Saturday, November 21, 2009

Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration.

29 Sep 2009 Exposure to cocaine causes many neuroadaptations including alterations in several neurotransmitter receptors and transporters. This study investigated potential mechanisms of cocaine-induced receptor and transporter regulation by measuring levels of ... Read more...

c-Fos expression associated with reinstatement of cocaine-seeking behavior by response-contingent conditioned cues.

29 Sep 2009 The capability of cocaine cues to generate craving in cocaine-dependent humans, even after extended abstinence, is modeled in rats using cue reinstatement of extinguished cocaine-seeking behavior. We investigated neural activity associated with ... Read more...

Attenuated behavioural responses to acute and chronic cocaine in GASP-1-deficient mice.

25 Aug 2009 G protein-coupled receptor (GPCR) associated sorting protein 1 (GASP-1) interacts with GPCRs and is implicated in their postendocytic sorting. Recently, GASP-1 has been shown to regulate dopamine (D(2)) and cannabinoid (CB1) receptor signalling, ... Read more...

Latest indexed articles for 'Dopamine Uptake Inhibitors - Administration & dosage'

These are the very latest articles for this heading:

• Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. 29 Sep 2009
• c-Fos expression associated with reinstatement of cocaine-seeking behavior by response-contingent conditioned cues. 29 Sep 2009
• Struck from behind: maintaining quality of life with chronic low back pain. 30 Aug 2009
• Attenuated behavioural responses to acute and chronic cocaine in GASP-1-deficient mice. 25 Aug 2009
• A smoking ban in public places increases the efficacy of bupropion and counseling on cessation outcomes at 1 year. 2 Aug 2009
• Yoked delivery of cocaine is aversive and protects against the motivation for drug in rats. 30 Jul 2009
• Acquisition of and withdrawal from cocaine self-administration regulates 5-HT mRNA expression in rat striatum. 28 Jul 2009
• Upregulation of GLT1 attenuates cue-induced reinstatement of cocaine-seeking behavior in rats. 20 Jul 2009
• Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function. 22 Jun 2009
• Khantzian's 'self-medication hypothesis' of drug addiction and films by Martin Scorsese. 30 May 2009
• Efficacy and safety of lacosamide in diabetic neuropathic pain: an 18-week double-blind placebo-controlled trial of fixed-dose regimens. 30 May 2009
• A 1-year safety and efficacy study of duloxetine in patients with fibromyalgia. 30 May 2009
• A randomized, controlled trial of bupropion sustained-release for preventing tobacco relapse in recovering alcoholics. 27 May 2009
• Prolonged withdrawal from repeated noncontingent cocaine exposure increases NMDA receptor expression and ERK activity in the nucleus accumbens. 25 May 2009
• Chronic cocaine enhances corticotropin-releasing factor-dependent potentiation of excitatory transmission in ventral tegmental area dopamine neurons. 18 May 2009
• Intra-accumbens shell injections of SR48692 enhanced cocaine self-administration intake in rats exposed to an environmentally-elicited reinstatement paradigm. 10 May 2009
• Treatment of comorbid tobacco use in people with serious mental illness. 29 Apr 2009
• Proteomic analysis of the nucleus accumbens of rats with different vulnerability to cocaine addiction. 20 Apr 2009
• Cocaine withdrawal enhances long-term potentiation in rat hippocampus via changing the activity of corticotropin-releasing factor receptor subtype 2. 15 Apr 2009
• Effects of cocaine self-administration history under limited and extended access conditions on in vivo striatal dopamine neurochemistry and acoustic startle in rhesus monkeys. 12 Apr 2009

See a longer list of these articles.

Technical information about 'Dopamine Uptake Inhibitors'

Definition: Drugs that block the transport of DOPAMINE into axon terminals or into storage vesicles within terminals. Most of the ADRENERGIC UPTAKE INHIBITORS also inhibit dopamine uptake.

Registry Number: 0

Descriptor UI: D018765

Alternative terms: Dopamine Uptake Inhibitors; Reuptake Inhibitors, Dopamine; Inhibitors, Dopamine Uptake; Uptake Inhibitors, Dopamine; Inhibitors, Dopamine Reuptake; Dopamine Reuptake Inhibitors;

Allowable Qualifiers: history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics;

Tree Number: D27.505.519.625.150.800; D27.505.519.625.600.220; D27.505.696.577.150.800; D27.505.696.577.600.220;

History Note: 95

Technical Notes: GEN or unspecified; prefer specifics; DF: DOPAMINE UPTAKE INHIB