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Dopamine Uptake Inhibitors
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Definition of 'Dopamine Uptake Inhibitors'

Drugs that block the transport of DOPAMINE into axon terminals or into storage vesicles within terminals. Most of the ADRENERGIC UPTAKE INHIBITORS also inhibit dopamine uptake.

Common names: Dopamine Uptake Inhibitors; Reuptake Inhibitors, Dopamine; Inhibitors, Dopamine Uptake; Uptake Inhibitors, Dopamine; Inhibitors, Dopamine Reuptake; Dopamine Reuptake Inhibitors

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Saturday, November 21, 2009

A neurocomputational model for cocaine addiction.

29 Sep 2009 Based on the dopamine hypotheses of cocaine addiction and the assumption of decrement of brain reward system sensitivity after long-term drug exposure, we propose a computational model for cocaine addiction. Utilizing average reward temporal ... Read more...


Varenicline and suicidal behaviour: a cohort study based on data from the General Practice Research Database.

29 Sep 2009 OBJECTIVE: To determine whether varenicline, a recently licensed smoking cessation product, is associated with an increased risk of suicide and suicidal behaviour compared with alternative treatments bupropion and nicotine replacement therapy. ... Read more...


In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand.

29 Sep 2009 This study evaluated the in vitro and in vivo characteristics of a new dopamine transporter (DAT) radioligand, [(18)F]fluoroethyl(FE)PE2I, by autoradiography from postmortem human brain and by positron emission tomography (PET) in three cynomolgus ... Read more...

 

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Technical information about 'Dopamine Uptake Inhibitors'

Definition: Drugs that block the transport of DOPAMINE into axon terminals or into storage vesicles within terminals. Most of the ADRENERGIC UPTAKE INHIBITORS also inhibit dopamine uptake.

Registry Number: 0

Descriptor UI: D018765

Alternative terms: Dopamine Uptake Inhibitors; Reuptake Inhibitors, Dopamine; Inhibitors, Dopamine Uptake; Uptake Inhibitors, Dopamine; Inhibitors, Dopamine Reuptake; Dopamine Reuptake Inhibitors;

Allowable Qualifiers: history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics;

Tree Number: D27.505.519.625.150.800; D27.505.519.625.600.220; D27.505.696.577.150.800; D27.505.696.577.600.220;

History Note: 95

Technical Notes: GEN or unspecified; prefer specifics; DF: DOPAMINE UPTAKE INHIB

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