Dose-Response Relationship, Drug
Research News and Information

Friday, November 20, 2009

Adrenal function testing in pediatric cancer survivors.

13 Dec 2009 BACKGROUND: Central adrenal insufficiency is observed after cranial radiation therapy for cancer. Screening at risk patients is recommended, but the best screening strategy is unknown. METHODS: A retrospective review of pediatric cancer survivors ... Read more...

The Viracept-EMS case: impact and outlook.

10 Nov 2009 This perspective first considers the potential impact of the Viracept-EMS case in the framework of the current understanding of the low-dose effects of DNA-reactive chemicals and the approaches used to estimate health risks from genotoxins occurring ... Read more...

Sustained antiretroviral effect of raltegravir after 96 weeks of combination therapy in treatment-naive patients with HIV-1 infection.

30 Oct 2009 OBJECTIVES: The purpose of this study was to evaluate the safety and efficacy of raltegravir vs efavirenz-based antiretroviral therapy after 96 weeks in treatment-naive patients with HIV-1 infection. METHODS: Multicenter, double-blind, randomized ... Read more...

Latest indexed articles for 'Dose-Response Relationship, Drug'

These are the very latest articles for this heading:

• Adrenal function testing in pediatric cancer survivors. 13 Dec 2009
• The Viracept-EMS case: impact and outlook. 10 Nov 2009
• Sustained antiretroviral effect of raltegravir after 96 weeks of combination therapy in treatment-naive patients with HIV-1 infection. 30 Oct 2009
• Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures. 30 Oct 2009
• Tonabersat, a gap-junction modulator: efficacy and safety in two randomized, placebo-controlled, dose-ranging studies of acute migraine. 30 Oct 2009
• "Above all, do no harm": hippocrates. 30 Oct 2009
• Perineural dexmedetomidine added to ropivacaine causes a dose-dependent increase in the duration of thermal antinociception in sciatic nerve block in rat. 30 Oct 2009
• Perinatal akathisia: implications for pharmacokinetic changes during pregnancy. 30 Oct 2009
• Endogenous opioids regulate expression of experimental autoimmune encephalomyelitis: a new paradigm for the treatment of multiple sclerosis. 30 Oct 2009
• Adequacy of vitamin D replacement in severe deficiency is dependent on body mass index. 30 Oct 2009
• A(1c) control in a primary care setting: self-titrating an insulin analog pre-mix (INITIATEplus trial). 30 Oct 2009
• Clinical policy: critical issues in the management of adult patients presenting to the emergency department with community-acquired pneumonia. 30 Oct 2009
• The effects of ultrasound guidance and neurostimulation on the minimum effective anesthetic volume of mepivacaine 1.5% required to block the sciatic nerve using the subgluteal approach. 30 Oct 2009
• A randomized comparison of low doses of hyperbaric bupivacaine in combined spinal-epidural anesthesia for cesarean delivery. 30 Oct 2009
• Volatile anesthetics attenuate oxidative stress-reduced activity of glutamate transporter type 3. 30 Oct 2009
• Propofol inhibits aquaporin 4 expression through a protein kinase C-dependent pathway in an astrocyte model of cerebral ischemia/reoxygenation. 30 Oct 2009
• The effects of sevoflurane and propofol on glucose metabolism under aerobic conditions in fed rats. 30 Oct 2009
• Acute methadone treatment reduces myocardial infarct size via the delta-opioid receptor in rats during reperfusion. 30 Oct 2009
• Neuraxial anesthesia for cesarean delivery: what criteria define the "optimal" technique? 30 Oct 2009
• Challenges in developing evidence-based drug dosing guidelines for adults and children receiving renal replacement therapy. 30 Oct 2009

See a longer list of these articles.

Technical information about 'Dose-Response Relationship, Drug'

Definition: The relationship between the dose of an administered drug and the response of the organism to the drug.

Descriptor UI: D004305

Alternative terms: Dose-Response Relationship, Drug; Dose-Response Relationships, Drug; Drug Dose-Response Relationship; Drug Dose-Response Relationships; Relationship, Drug Dose-Response; Relationships, Drug Dose-Response; Dose Response Relationship, Drug;

Tree Number: G07.690.220;

History Note: 73

Technical Notes: no qualif; IM if general, NIM when coord for specific drug; DF: DOSE RESPONSE RELAT DRUG