Drug Combinations
Research News and Information

Saturday, November 21, 2009

A randomized, placebo-controlled, dose-escalation study to determine the safety, tolerability, and immunogenicity of an HPV-16 therapeutic vaccine in HIV-positive participants with oncogenic HPV infection of the anus.

30 Oct 2009 OBJECTIVE: Study aimed to assess safety, tolerability, and immunogenicity of novel therapeutic HPV-16 E6E7 ISCOMATRIX vaccine for treatment of human papilloma virus (HPV)-related anal intraepithelial neoplasia in HIV-infected men who have sex with ... Read more...

An ultra-low dose of naloxone added to lidocaine or lidocaine-fentanyl mixture prolongs axillary brachial plexus blockade.

30 Oct 2009 INTRODUCTION: In this prospective, randomized, double-blind study, we evaluated the effect of an ultra-low dose of naloxone added to lidocaine and fentanyl mixture on the onset and duration of axillary brachial plexus block. METHODS: One hundred ... Read more...

Prostaglandin E2-induced masculinization of brain and behavior requires protein kinase A, AMPA/kainate, and metabotropic glutamate receptor signaling.

19 Oct 2009 Prostaglandin E(2) (PGE(2)) mediates the masculinization of adult sex behavior in rats in response to the surge in serum testosterone at approximately birth. Measures of behavioral masculinization correlate with a twofold increase in spinophilin ... Read more...

Latest indexed articles for 'Drug Combinations'

These are the very latest articles for this heading:

• A randomized, placebo-controlled, dose-escalation study to determine the safety, tolerability, and immunogenicity of an HPV-16 therapeutic vaccine in HIV-positive participants with oncogenic HPV infection of the anus. 30 Oct 2009
• An ultra-low dose of naloxone added to lidocaine or lidocaine-fentanyl mixture prolongs axillary brachial plexus blockade. 30 Oct 2009
• Comparison between dexmedetomidine and remifentanil for intraoperative controlled hypotension. 30 Oct 2009
• Artemisinin resistance on the Thai-Cambodian border. 22 Oct 2009
• Artemisinin resistance on the Thai-Cambodian border. 22 Oct 2009
• Prostaglandin E2-induced masculinization of brain and behavior requires protein kinase A, AMPA/kainate, and metabotropic glutamate receptor signaling. 19 Oct 2009
• Protein kinase C mediates the synergistic interaction between agonists acting at alpha2-adrenergic and delta-opioid receptors in spinal cord. 19 Oct 2009
• STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitro. 13 Oct 2009
• Reflections: neurology and the humanities: reflections for October. 11 Oct 2009
• Mefloquine has more adverse effects than other drugs for malaria prophylaxis. 11 Oct 2009
• Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms. 5 Oct 2009
• Clinical experience in treating hypertension with fixed-dose combination therapy: angiotensin II receptor blocker losartan plus hydrochlorothiazide. 29 Sep 2009
• The clinical efficacy and abuse potential of combination buprenorphine-naloxone in the treatment of opioid dependence. 29 Sep 2009
• Combination therapy for obesity and metabolic disease. 29 Sep 2009
• S-1 mediates the inhibition of lymph node metastasis in oral cancer cells. 29 Sep 2009
• Anabolic actions of IGF-I and TGF-beta1 on Interleukin-1beta-treated human articular chondrocytes: evaluation in two and three dimensional cultures. 29 Sep 2009
• Pars plana vitrectomy alone with diffuse illumination and vitreous dissection to manage primary retinal detachment with unseen breaks. 29 Sep 2009
• Tachosil: a new alternative for the treatment of non-traumatic corneal perforations. 29 Sep 2009
• Carbon-ion beam irradiation effectively suppresses migration and invasion of human non-small-cell lung cancer cells. 29 Sep 2009
• Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Drug Combinations'

Definition: Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.

Registry Number: 0

Descriptor UI: D004338

Alternative terms: Drug Combinations; Combinations, Drug;

Related Mesh Headings: Drug Synergism; Drug Therapy, Combination;

Tree Number: D26.310;

History Note: 73(71)

Technical Notes: IM for general only; NIM with specific drugs; differentiate from DRUG THERAPY, COMBINATION: drug combinations = 2 or more drugs in a single dosage form; combination ther = 2 or more drugs separately for a combined eff;