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Drug Hypersensitivity - Immunology
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Definition of 'Drug Hypersensitivity'

Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Common names: Drug Hypersensitivity; Drug Hypersensitivities; Hypersensitivities, Drug; Drug Allergy; Allergies, Drug; Drug Allergies; Hypersensitivity, Drug; Allergy, Drug

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Saturday, November 21, 2009

Modulation by aspirin of nuclear phospho-signal transducer and activator of transcription 6 expression: Possible role in therapeutic benefit associated with aspirin desensitization.

17 Sep 2009 BACKGROUND: Aspirin-exacerbated respiratory disease is characterized by asthma, nasal polyps, and intolerance to aspirin with overexpression of leukotriene (LT) C(4) synthase and cysteinyl leukotriene receptors. Through an unknown mechanism, aspirin ... Read more...


Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.

17 Sep 2009 BACKGROUND: NLR family, pyrin domain containing 3 (NLRP3), controls the activity of inflammatory caspase-1 by forming inflammasomes, which leads to cleavage of the procytokines IL-1beta and IL-18. Recent studies have shown associations of human ... Read more...


Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization.

30 Aug 2009 BACKGROUND: Staphylococcus aureus (SA) in the nose can be a simple colonizer but also may create an intramucosal reservoir causing recurrent infections or can be a specific immune modulator through superantigenic mechanisms. Because the colonization ... Read more...

 

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Technical information about 'Drug Hypersensitivity'

Definition: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Descriptor UI: D004342

Alternative terms: Drug Hypersensitivity; Drug Hypersensitivities; Hypersensitivities, Drug; Drug Allergy; Allergies, Drug; Drug Allergies; Hypersensitivity, Drug; Allergy, Drug;

Allowable Qualifiers: blood; cerebrospinal fluid; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C20.543.206;

History Note: 66; was DRUG ALLERGY 1963-65

Technical Notes: use in conventional sense and not for allergy to every category D term; allergy to non-drug chemical substance=substance /ad eff + HYPERSENSITIVITY or its specifics /etiol; manual 23.24+

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