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Drug Resistance, Microbial
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Definition of 'Drug Resistance, Microbial'

The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).

Common names: Drug Resistance, Microbial; Drug Resistances, Microbial; Antimicrobial Drug Resistance; Antimicrobial Drug Resistances; Antibiotic Resistance, Microbial; Antibiotic Resistance; Resistance, Antibiotic

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Sunday, November 22, 2009

Epidemiology and susceptibilities of methicillin-resistant Staphylococcus aureus in Northeastern Ohio.

30 Oct 2009 A retrospective survey was performed on all staphylococcal infections diagnosed by the Ashtabula County Medical Center (Ashtabula, OH) during 2006 and 2007. Of the 1,612 Staphylococcus aureus isolates evaluated for their antibiotic resistances, 947 ... Read more...


Biochemical characterization of the multidrug regulator QacR distinguishes residues that are crucial to multidrug binding and induction of qacA transcription.

18 Oct 2009 Staphylococcus aureus transcription factor QacR regulates expression of the qacA multidrug efflux determinant. In response to binding cationic lipophilic compounds, including ethidium and rhodamine 6G, QacR dissociates from the qacA operator ... Read more...


Antibiotic resistance in community-acquired pneumonia caused by Streptococcus pneumoniae, methicillin-resistant Staphylococcus aureus, and Acinetobacter baumannii.

29 Sep 2009 Antimicrobial therapy is the mainstay of management for community-acquired pneumonia (CAP). Accordingly, the choices of treatment are influenced by the likely etiologies, local resistance patterns of the pathogens, as well as patient factors. As the ... Read more...

 

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Technical information about 'Drug Resistance, Microbial'

Definition: The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).

Descriptor UI: D004352

Alternative terms: Drug Resistance, Microbial; Drug Resistances, Microbial; Antimicrobial Drug Resistance; Antimicrobial Drug Resistances; Antibiotic Resistance, Microbial; Antibiotic Resistance; Resistance, Antibiotic;

Related Mesh Headings: Microbial Sensitivity Tests; R Factors; Superinfection; Tuberculosis, Multidrug-Resistant;

Allowable Qualifiers: ethnology; genetics; immunology; physiology; radiation effects;

Tree Number: G06.225; G07.690.320.269;

History Note: 1963; for ANTIBIOTIC RESISTANCE use DRUG RESISTANCE 2002-2007

Technical Notes: general or unspecified; prefer specifics; not for protozoa: index DRUG RESISTANCE

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