Drug Resistance
Research News and Information

Sunday, November 22, 2009

Postoperative nonconvulsive encephalopathic status: identification of a syndrome responsible for delayed progressive deterioration of neurological status after skull base surgery. Clinical article.

30 Oct 2009 OBJECT: Over a 10-year period, the authors have observed a rare but recurring syndrome manifested by a delayed, postoperative, progressive decline in the level of consciousness to deep coma that is time-limited to several days with abrupt awakening. ... Read more...

A pre-emptive strike against malaria's stealthy hepatic forms.

30 Oct 2009 Almost all the drugs that are widely used today against Plasmodium spp., the causative agent of malaria, target the asexual blood stages of the parasite. Widespread drug resistance severely restricts our ability to control malaria and makes it ... Read more...

New medicines to improve control and contribute to the eradication of malaria.

14 Oct 2009 Despite being one of the most prevalent tropical diseases, for many years malaria was not a commercial priority for the pharmaceutical industry. However, in response to the emergence and spread of resistance to the available antimalarial drugs, ... Read more...

Latest indexed articles for 'Drug Resistance'

These are the very latest articles for this heading:

• Postoperative nonconvulsive encephalopathic status: identification of a syndrome responsible for delayed progressive deterioration of neurological status after skull base surgery. Clinical article. 30 Oct 2009
• A pre-emptive strike against malaria's stealthy hepatic forms. 30 Oct 2009
• Malaria: a research agenda for the eradication era. 29 Oct 2009
• Artemisinin resistance in Plasmodium falciparum malaria. 27 Oct 2009
• Artemisinin resistance in Plasmodium falciparum malaria. 27 Oct 2009
• Artemisinin resistance on the Thai-Cambodian border. 22 Oct 2009
• Artemisinin resistance on the Thai-Cambodian border. 22 Oct 2009
• New medicines to improve control and contribute to the eradication of malaria. 14 Oct 2009
• Mefloquine has more adverse effects than other drugs for malaria prophylaxis. 11 Oct 2009
• Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance. 6 Oct 2009
• [Drug-resistant epilepsy] 6 Oct 2009
• [Adalimumab treatment in infliximab-resistant pediatric patient with Crohn's disease] 2 Oct 2009
• Shifting paradigms: the seeds of oncogene addiction. 29 Sep 2009
• Sexual dimorphism: Is it relevant to steroid resistance or asthma control? 29 Sep 2009
• Seizure relapse and development of drug resistance following long-term seizure remission. 29 Sep 2009
• Biological resistance of hydroxychloroquine for Plasmodium vivax malaria in the Republic of Korea. 29 Sep 2009
• Glucocorticoid sensitivity of lipopolysaccharide-stimulated chronic obstructive pulmonary disease alveolar macrophages. 29 Sep 2009
• Chloroquine transport via the malaria parasite's chloroquine resistance transporter. 23 Sep 2009
• Severe cardiac failure in a patient with multiple sclerosis following low-dose mitoxantrone treatment. 20 Sep 2009
• Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial. 14 Sep 2009

See a longer list of these articles.

Technical information about 'Drug Resistance'

Definition: Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.

Descriptor UI: D004351

Alternative terms: Drug Resistance; Resistance, Drug;

Related Mesh Headings: Pharmacogenetics;

Allowable Qualifiers: ethnology; genetics; immunology; physiology; radiation effects; drug effects;

Tree Number: G07.690.320;

History Note: 1972

Technical Notes: general or unspecified; prefer specifics; differentiate from DRUG TOLERANCE; resistance of parasites including protozoa goes here