Dupuytren's Contracture - Metabolism
Research News and Information

Sunday, November 22, 2009

Type-1 Collagen differentially alters beta-catenin accumulation in primary Dupuytren's Disease cord and adjacent palmar fascia cells.

17 Jun 2009 BACKGROUND: Dupuytren's Disease (DD) is a debilitating contractile fibrosis of the palmar fascia characterised by excess collagen deposition, contractile myofibroblast development, increased transforming growth factor-beta levels and beta-catenin ... Read more...

[The pathobiochemistry of Dupuytren's contracture]

27 Feb 2009 Dupuytren's contracture is a connective tissue disorder characterized by nodular fibroblastic proliferation of palmar fascia leading to a shortening and progressive digital flexion deformity. It seems that this pathological process is initiated by ... Read more...

An integrated proteomics approach for studying the molecular pathogenesis of Dupuytren's disease.

27 Feb 2009 Dupuytren's disease (DD) is a fibromatosis characterized by non-malignant transformation of palmar fascia leading to permanent contraction of one or more fingers. Despite the extensive knowledge of its clinical pathogenesis, the aetiology of this ... Read more...

Latest indexed articles for 'Dupuytren's Contracture - Metabolism'

These are the very latest articles for this heading:

• Type-1 Collagen differentially alters beta-catenin accumulation in primary Dupuytren's Disease cord and adjacent palmar fascia cells. 17 Jun 2009
• [The pathobiochemistry of Dupuytren's contracture] 27 Feb 2009
• An integrated proteomics approach for studying the molecular pathogenesis of Dupuytren's disease. 27 Feb 2009
• Identification of biomarkers in Dupuytren's disease by comparative analysis of fibroblasts versus tissue biopsies in disease-specific phenotypes. 30 Dec 2008
• Immunohistochemical evidence for Zic1 coexpression with beta-catenin in the myofibroblast of Dupuytren disease. 30 Dec 2008
• Beta-catenin overexpression in Dupuytren's disease is unrelated to disease recurrence. 27 Oct 2008
• Lack of association of iron metabolism and Dupuytren's disease. 8 Jan 2008
• Enhanced alpha 1(I) mRNA expression in frozen shoulder and dupuytren tissue. 12 Dec 2007
• Dermatan sulfate remodeling associated with advanced Dupuytren's contracture. 7 Dec 2007
• [Role of fibroblasts in physiologic, reparative and pathologic processes] 7 Sep 2007
• The expression of myoglobin and ROR2 protein in Dupuytren's disease. 18 Aug 2007
• Dupuytren's disease involving the wrist. 27 Feb 2007
• Immunohistochemical evidence of nerve growth factor in Dupuytren's diseased palmar fascia. 27 Feb 2007
• Beta-catenin signaling in fibroproliferative disease. 13 Nov 2006
• Factors in the pathogenesis of Dupuytren's contracture. 30 Oct 2006
• Wnt expression is not correlated with beta-catenin dysregulation in Dupuytren's Disease. 28 Aug 2006
• Feedback inhibition of high TGF-beta1 concentrations on myofibroblast induction and contraction by Dupuytren's fibroblasts. 24 Jul 2006
• Identification of protein biomarkers in Dupuytren's contracture using surface enhanced laser desorption ionization time-of-flight mass spectrometry (SELDI-TOF-MS). 30 May 2006
• [Clonality study of palmar fibromatosis] 30 Mar 2006
• Increased metabolic activity of fibroblasts derived from cords compared with nodule fibroblasts sampling from patients with Dupuytren's contracture. 30 Mar 2006

See a longer list of these articles.

Technical information about 'Dupuytren's Contracture'

Definition: A fibromatosis of the palmar fascia characterized by thickening and contracture of the fibrous bands on the palmar surfaces of the hand and fingers. It arises most commonly in men between the ages of 30 and 50.

Descriptor UI: D004387

Alternative terms: Dupuytren's Contracture; Contracture, Dupuytren's; Dupuytren Contracture; Dupuytrens Contracture;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C05.651.197.270; C17.300.270;

Technical Notes: contracture of fingers