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Ear, Inner - Drug effects
Research News and Information
Definition of 'Ear, Inner'The essential part of the hearing organ consists of two labyrinthine compartments: the bony labyrinthine and the membranous labyrinth. The bony labyrinth is a complex of three interconnecting cavities or spaces (COCHLEA; VESTIBULAR LABYRINTH; and SEMICIRCULAR CANALS) in the TEMPORAL BONE. Within the bony labyrinth lies the membranous labyrinth which is a complex of sacs and tubules (COCHLEAR DUCT; SACCULE AND UTRICLE; and SEMICIRCULAR DUCTS) forming a continuous space enclosed by EPITHELIUM and connective tissue. These spaces are filled with LABYRINTHINE FLUIDS of various compositions. |
Sunday, November 22, 2009
Safety of high-dose corticosteroids for the treatment of autoimmune inner ear disease.
30 May 2009 
OBJECTIVE: To report the adverse effects associated with prolonged high-dose prednisone for the treatment of autoimmune inner ear disease (AIED). STUDY DESIGN: Prospective data collected as part of a multicenter, randomized, controlled trial for the ... Read more...
8 May 2009 Inner ear damage may lead to structural changes in the central auditory system. In rat and chinchilla, cochlear ablation and noise trauma result in fiber growth and synaptogenesis in the ventral cochlear nucleus (VCN). In this study, we documented ... Read more...
May 2009 Recent data show that hormone replacement therapy, involving estrogen together with progestin, can promote hearing loss (Guimaraes, P., Frisina, S.T., Mapes, F., Tadros, S.F., Frisina, D.R. and Frisina, R.D., 2006. Progestin negatively affects ... Read more...
Latest indexed articles for 'Ear, Inner - Drug effects'
These are the very latest articles for this heading:
- Safety of high-dose corticosteroids for the treatment of autoimmune inner ear disease. 30 May 2009
- Central auditory plasticity after carboplatin-induced unilateral inner ear damage in the chinchilla: up-regulation of GAP-43 in the ventral cochlear nucleus. 8 May 2009
- Effect of chronic estradiol administration on vimentin and GFAP immunohistochemistry within the inner ear. May 2009
- Steroid control of acute middle ear inflammation in a mouse model. 29 Apr 2009
- The detection of pressure fluctuations, sonic audition, is the dominant mode of dipole-source detection in goldfish (Carassius auratus). 30 Mar 2009
- Effect of inner ear blood flow changes in Ménière's model mice. 27 Feb 2009
- Effects of glycerol intake and body tilt on otoacoustic emissions reflect labyrinthine pressure changes in Menière's disease. 30 Jan 2009
- Changes in transient receptor potential vanilloid (TRPV) 1, 2, 3 and 4 expression in mouse inner ear following gentamicin challenge. 30 Jan 2009
- Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium. 12 Jan 2009
- Radical scavengers for elderly patients with age-related hearing loss. 30 Dec 2008
- Aquaporins as potential drug targets for Meniere's disease and its related diseases. 30 Dec 2008
- Vestibular neurectomy vs. chemical labyrinthectomy in the treatment of disabling Menière's disease: a long-term comparative study. 18 Nov 2008
- The possible role of proton pump inhibitors of the homeostasis of the inner ear. 18 Nov 2008
- Ototoxicity and otoprotection in the inner ear of guinea pigs using gentamicin and amikacin: ultrastructural and functional aspects.
30 Oct 2008 - Novel drug delivery systems for inner ear protection and regeneration after hearing loss. 29 Sep 2008
- Considerations on the physiopathological mechanism of inner ear damage induced by intravenous cocaine abuse: cues from a case report. 12 Jul 2008
- Proteomic analysis of the balance between survival and cell death responses in cisplatin-mediated ototoxicity. 24 Jun 2008
- In reference to visualization of endolymphatic hydrops in patients with Meniere's disease.
29 Apr 2008 - Investigation of the effects of PACAP on the composition of tear and endolymph proteins. 16 Apr 2008
- Effects of systemic versus local gentamicin on the inner ear in the Atlantic cod, Gadus morhua (L.), relevance for fish hearing investigations. 5 Apr 2008
See a longer list of these articles.
Technical information about 'Ear, Inner'
Definition: The essential part of the hearing organ consists of two labyrinthine compartments: the bony labyrinthine and the membranous labyrinth. The bony labyrinth is a complex of three interconnecting cavities or spaces (COCHLEA; VESTIBULAR LABYRINTH; and SEMICIRCULAR CANALS) in the TEMPORAL BONE. Within the bony labyrinth lies the membranous labyrinth which is a complex of sacs and tubules (COCHLEAR DUCT; SACCULE AND UTRICLE; and SEMICIRCULAR DUCTS) forming a continuous space enclosed by EPITHELIUM and connective tissue. These spaces are filled with LABYRINTHINE FLUIDS of various compositions.
Descriptor UI: D007758
Alternative terms: Ear, Inner; Ears, Inner; Inner Ears; Inner Ear; Labyrinth; Labyrinths; Ear, Internal; Ears, Internal; Internal Ear; Internal Ears; Membranous Labyrinth; Labyrinth, Membranous; Labyrinths, Membranous; Membranous Labyrinths; Bony Labyrinth; Bony Labyrinths; Labyrinth, Bony; Labyrinths, Bony;
Related Mesh Headings: Endolymph;
Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;
Tree Number: A09.246.631;
History Note: 2006 (1963)
Technical Notes: /inj: pressure-induced injuries = EAR, INNER / inj (IM) + BAROTRAUMA (IM), noise-induced injuries = HEARING LOSS, NOISE-INDUCED; inflammation = LABYRINTHITIS; neoplasms = LABYRINTH DISEASES (IM) + EAR NEOPLASMS (IM) + histological type of neoplasm (IM)