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Ear, Inner - Physiology
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Definition of 'Ear, Inner'

The essential part of the hearing organ consists of two labyrinthine compartments: the bony labyrinthine and the membranous labyrinth. The bony labyrinth is a complex of three interconnecting cavities or spaces (COCHLEA; VESTIBULAR LABYRINTH; and SEMICIRCULAR CANALS) in the TEMPORAL BONE. Within the bony labyrinth lies the membranous labyrinth which is a complex of sacs and tubules (COCHLEAR DUCT; SACCULE AND UTRICLE; and SEMICIRCULAR DUCTS) forming a continuous space enclosed by EPITHELIUM and connective tissue. These spaces are filled with LABYRINTHINE FLUIDS of various compositions.

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Monday, November 23, 2009

Chondrocyte-specific Smad4 gene conditional knockout results in hearing loss and inner ear malformation in mice.

30 Jul 2009 Smad4 is the central intracellular mediator of transforming growth factor-beta (TGF-beta) signaling, which plays crucial roles in tissue regeneration, cell differentiation, embryonic development, and regulation of the immune system. Conventional ... Read more...


Cochlear third window in the scala vestibuli: an animal model.

30 Jul 2009 BACKGROUND: Pathologic third window has been investigated in both animals and humans, with a third window located in the vestibular apparatus, specifically, dehiscence of the superior semicircular canal, serving as the clinical model. HYPOTHESIS: ... Read more...


Development and regeneration of the inner ear.

29 Jun 2009 Loss of sensory hair cells is the leading cause of deafness in humans. The mammalian cochlea cannot regenerate its complement of sensory hair cells. Thus at present, the only treatment for deafness due to sensory hair cell loss is the use of ... Read more...

 

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Technical information about 'Ear, Inner'

Definition: The essential part of the hearing organ consists of two labyrinthine compartments: the bony labyrinthine and the membranous labyrinth. The bony labyrinth is a complex of three interconnecting cavities or spaces (COCHLEA; VESTIBULAR LABYRINTH; and SEMICIRCULAR CANALS) in the TEMPORAL BONE. Within the bony labyrinth lies the membranous labyrinth which is a complex of sacs and tubules (COCHLEAR DUCT; SACCULE AND UTRICLE; and SEMICIRCULAR DUCTS) forming a continuous space enclosed by EPITHELIUM and connective tissue. These spaces are filled with LABYRINTHINE FLUIDS of various compositions.

Descriptor UI: D007758

Alternative terms: Ear, Inner; Ears, Inner; Inner Ears; Inner Ear; Labyrinth; Labyrinths; Ear, Internal; Ears, Internal; Internal Ear; Internal Ears; Membranous Labyrinth; Labyrinth, Membranous; Labyrinths, Membranous; Membranous Labyrinths; Bony Labyrinth; Bony Labyrinths; Labyrinth, Bony; Labyrinths, Bony;

Related Mesh Headings: Endolymph;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A09.246.631;

History Note: 2006 (1963)

Technical Notes: /inj: pressure-induced injuries = EAR, INNER / inj (IM) + BAROTRAUMA (IM), noise-induced injuries = HEARING LOSS, NOISE-INDUCED; inflammation = LABYRINTHITIS; neoplasms = LABYRINTH DISEASES (IM) + EAR NEOPLASMS (IM) + histological type of neoplasm (IM)

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