Early Growth Response Protein 1 - Metabolism
Research News and Information

Monday, November 23, 2009

Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent.

14 Oct 2009 alphabeta and gammadelta T cells arise from a common thymocyte progenitor during development in the thymus. Emerging evidence suggests that the pre-T cell receptor (pre-TCR) and gammadelta T cell receptor (gammadeltaTCR) play instructional roles in ... Read more...

An integrated systems analysis implicates EGR1 downregulation in simian immunodeficiency virus encephalitis-induced neural dysfunction.

5 Oct 2009 Human immunodeficiency virus (HIV)-associated dementia (HAD) is a syndrome occurring in HIV-infected patients with advanced disease that likely develops as a result of macrophage and microglial activation as well as other immune events triggered by ... Read more...

Enhanced radiosensitivity of SW480 cells via TRAIL up-regulation mediated by Egr-1 promoter.

29 Sep 2009 Radiosensitization of cancer cells to irradiation could improve the efficacy of radiotherapy. The early transcriptional factor (Egr-1) promoter induced expression of downstream genes after irradiation. TNF-related apoptosis-inducing ligand (TRAIL) ... Read more...

Latest indexed articles for 'Early Growth Response Protein 1 - Metabolism'

These are the very latest articles for this heading:

• Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent. 14 Oct 2009
• An integrated systems analysis implicates EGR1 downregulation in simian immunodeficiency virus encephalitis-induced neural dysfunction. 5 Oct 2009
• Enhanced radiosensitivity of SW480 cells via TRAIL up-regulation mediated by Egr-1 promoter. 29 Sep 2009
• Differential responsiveness in brain and behavior to sexually dimorphic long calls in male and female zebra finches. 29 Sep 2009
• Deletion of caveolin-1 protects hyperoxia-induced apoptosis via survivin-mediated pathways. 16 Sep 2009
• Regulated expression of the alpha isoform of the human thromboxane A2 receptor during megakaryocyte differentiation: a coordinated role for WT1, Egr1, and Sp1. 6 Sep 2009
• A novel anticancer effect of Astragalus saponins: Transcriptional activation of NSAID-activated gene. 30 Aug 2009
• Granular and dysgranular retrosplenial cortices provide qualitatively different contributions to spatial working memory: evidence from immediate-early gene imaging in rats. 25 Aug 2009
• High-mobility group box 1 protein induces tissue factor expression in vascular endothelial cells via activation of NF-kappaB and Egr-1. 30 Jul 2009
• Induction of apoptosis and nonsteroidal anti-inflammatory drug-activated gene 1 in pancreatic cancer cells by a glycyrrhetinic acid derivative. 30 Jul 2009
• The fibrotic phenotype induced by IGFBP-5 is regulated by MAPK activation and egr-1-dependent and -independent mechanisms. 21 Jul 2009
• Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes. 14 Jul 2009
• Egr-1, the potential target of calcium channel blockers in cardioprotection with ischemia/reperfusion injury in rats. 29 Jun 2009
• Changes in the proteome after neuronal zif268 overexpression. 29 Jun 2009
• Transcriptional regulation of the murine Presenilin-2 gene reveals similarities and differences to its human orthologue. 28 Jun 2009
• Identification of a novel DNA binding site and a transcriptional target for activating transcription factor 5 in c6 glioma and mcf-7 breast cancer cells. 14 Jun 2009
• Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer. 9 Jun 2009
• T-bet expression is regulated by EGR1-mediated signaling in activated T cells. 30 May 2009
• Early growth response 1 loops the CYP2B6 promoter for synergistic activation by the distal and proximal nuclear receptors CAR and HNF4alpha. 21 May 2009
• A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer. 10 May 2009

See a longer list of these articles.

Technical information about 'Early Growth Response Protein 1'

Definition: An early growth response transcription factor that has been implicated in regulation of CELL PROLIFERATION and APOPTOSIS.

Registry Number: 0

Descriptor UI: D051766

Alternative terms: Early Growth Response Protein 1; EGR1 Transcription Factor; Transcription Factor, EGR1; Early Growth Response Transcription Factor 1;

Allowable Qualifiers: standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists; administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion;

Tree Number: D12.776.260.158.500; D12.776.460.525.500; D12.776.930.313.500;

History Note: 2006(1988)