Endothelium, Vascular - Drug effects
Research News and Information

Sunday, November 22, 2009

Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability.

29 Nov 2009 Up to date, the nature of the sepsis-induced vascular leakage is understood only partially, which limits pharmacological approaches for its management. Here we studied the protective effect of cAMP using endotoxin-induced hyperpermeability as a ... Read more...

Endothelial cells incubated with platelet-rich plasma express PDGF-B and ICAM-1 and induce bone marrow stromal cell migration.

30 Oct 2009 Platelet-rich plasma (PRP) is used to accelerate bone repair through the growth factors released by platelets. The purpose of this study was to evaluate if PRP induce human umbilical vein endothelial cells (HUVEC) to express mRNA for osteogenic ... Read more...

Nebivolol: the somewhat-different beta-adrenergic receptor blocker.

11 Oct 2009 Although its clinical use in Europe dates almost 10 years, nebivolol is a beta-blocker that has been only recently introduced in the U.S. market. Like carvedilol, nebivolol belongs to the third generation of beta-blockers, which possess direct ... Read more...

Latest indexed articles for 'Endothelium, Vascular - Drug effects'

These are the very latest articles for this heading:

• Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability. 29 Nov 2009
• Endothelial cells incubated with platelet-rich plasma express PDGF-B and ICAM-1 and induce bone marrow stromal cell migration. 30 Oct 2009
• Nebivolol: the somewhat-different beta-adrenergic receptor blocker. 11 Oct 2009
• Hepatocyte gp130 deficiency reduces vascular remodeling after carotid artery ligation. 3 Oct 2009
• Immunotherapy for multiple sclerosis: the curious case of interferon beta. 29 Sep 2009
• The vasculature emerges as a potential therapeutic target in treating ADPKD liver cysts. 29 Sep 2009
• Evidence for the association of peroxidases with the antioxidant effect of p-coumaric acid in endothelial cells exposed to high glucose plus arachidonic acid. 28 Sep 2009
• Ghrelin restores the endothelin 1/nitric oxide balance in patients with obesity-related metabolic syndrome. 26 Sep 2009
• Exogenous ghrelin on nitric oxide-endothelin 1 imbalance in metabolic syndrome: can we kill 2 birds with 1 stone? 26 Sep 2009
• A new PIXel in the puzzle: how increased vascular pressure induces oxidative stress. 19 Sep 2009
• eNOS uncoupling and endothelial dysfunction in aged vessels. 16 Sep 2009
• Role of renin-angiotensin system blockade in patients with diabetes mellitus. 13 Sep 2009
• Absence of adenosine-mediated aortic relaxation in A(2A) adenosine receptor knockout mice. 9 Sep 2009
• Potassium inhibits dietary salt-induced transforming growth factor-beta production. 6 Sep 2009
• Docosahexaenoic acid down-regulates endothelial Nox 4 through a sPLA2 signalling pathway. 4 Sep 2009
• Varicose veins show enhanced chemokine expression. 31 Aug 2009
• Impact of the transfer of sFlt-1 gene fragments on the ERK1/2 pathway of VEGF in vitro. 30 Aug 2009
• Lactosylceramide causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells. 30 Aug 2009
• Asymmetric dimethylarginine endogenous inhibition of nitric oxide synthase causes differential vasculature effects. 30 Aug 2009
• Effects of biologics on vascular function and atherosclerosis associated with rheumatoid arthritis. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Endothelium, Vascular'

Definition: Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components from interstitium to lumen; this function has been most intensively studied in the blood capillaries.

Descriptor UI: D004730

Alternative terms: Endothelium, Vascular; Vascular Endothelium; Endotheliums, Vascular; Vascular Endotheliums; Capillary Endothelium; Capillary Endotheliums; Endothelium, Capillary; Endotheliums, Capillary;

Allowable Qualifiers: abnormalities; anatomy & histology; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A07.231.330; A10.272.491.355;

History Note: 88