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Endpoint Determination
Research News and Information
Definition of 'Endpoint Determination'Establishment of the level of a quantifiable effect indicative of a biologic process. The evaluation is frequently to detect the degree of toxic or therapeutic effect. Common names: Endpoint Determination; Determination, Endpoint; Determinations, Endpoint; Endpoint Determinations; End Point Determination; Determinations, End Point; End Point Determinations; Point Determinations, End; Endpoint Assay; Assay, Endpoint; Assays, Endpoint; Endpoint Assays; End Point Assay |
Monday, November 23, 2009
Biological effects of high-energy neutrons measured in vivo using a vertebrate model.
29 Sep 2009 
Interaction of solar protons and galactic cosmic radiation with the atmosphere and other materials produces high-energy secondary neutrons from below 1 to 1000 MeV and higher. Although secondary neutrons may provide an appreciable component of the ... Read more...
High content analysis of human fibroblast cell cultures after exposure to space radiation.
29 Sep 2009 Space travel imposes risks to human health, in large part by the increased radiation levels compared to those on Earth. To understand the effects of space radiation on humans, it is important to determine the underlying cellular mechanisms. While ... Read more...
Randomized, controlled trial of telcagepant for the acute treatment of migraine.
20 Sep 2009 BACKGROUND: The neuropeptide calcitonin gene-related peptide (CGRP) plays a key role in migraine pathophysiology. In this large phase 3 clinical trial, we sought to confirm the efficacy of telcagepant, the first orally bioavailable CGRP receptor ... Read more...
Latest indexed articles for 'Endpoint Determination'
These are the very latest articles for this heading:
- Biological effects of high-energy neutrons measured in vivo using a vertebrate model. 29 Sep 2009
- High content analysis of human fibroblast cell cultures after exposure to space radiation. 29 Sep 2009
- Randomized, controlled trial of telcagepant for the acute treatment of migraine. 20 Sep 2009
- Novel evidence-based systemic lupus erythematosus responder index. 13 Sep 2009
- A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus. 13 Sep 2009
- OARSI/OMERACT criteria of being considered a candidate for total joint replacement in knee/hip osteoarthritis as an endpoint in clinical trials evaluating potential disease modifying osteoarthritic drugs. 30 Aug 2009
- Skeletal health: primate model of postmenopausal osteoporosis. 30 Aug 2009
- Defining and labeling disease-modifying treatments for Alzheimer's disease. 30 Aug 2009
- Development of criteria for evaluating clinical response in thyroid eye disease using a modified Delphi technique. 30 Aug 2009
- Contact-free infrared thermography for assessing effects during acupuncture: a randomized, single-blinded, placebo-controlled crossover clinical trial. 30 Aug 2009
- Dreaming and electroencephalographic changes during anesthesia maintained with propofol or desflurane. 30 Aug 2009
- Progression-free survival in bevacizumab-based first-line treatment for patients with metastatic colorectal cancer: is it a really good end point?
29 Aug 2009 - Neurological and neurobehavioral assessment of experimental subarachnoid hemorrhage. 23 Aug 2009
- Primary End Point (Six Months) Results of the Ranibizumab for Edema of the mAcula in diabetes (READ-2) study. 20 Aug 2009
- Protocol for a randomized controlled trial on risk adapted damage control orthopedic surgery of femur shaft fractures in multiple trauma patients. 17 Aug 2009
- From trial and error to trial simulation. Part 2: an appraisal of current beliefs in the design and analysis of clinical trials for antidepressant drugs. 10 Aug 2009
- Stent-protected angioplasty in asymptomatic carotid artery stenosis vs. endarterectomy: SPACE2 - a three-arm randomised-controlled clinical trial. 30 Jul 2009
- Recent European Food Safety Authority toxicological evaluations of major phthalates used in food contact materials. 30 Jul 2009
- Efficacy and safety of prescription omega-3-acid ethyl esters for the prevention of recurrent symptomatic atrial fibrillation: a prospective study. 30 Jul 2009
- Effects of cancer drugs on survival: often poorly evaluated. 30 Jul 2009
See a longer list of these articles.
Technical information about 'Endpoint Determination'
Definition: Establishment of the level of a quantifiable effect indicative of a biologic process. The evaluation is frequently to detect the degree of toxic or therapeutic effect.
Descriptor UI: D023381
Alternative terms: Endpoint Determination; Determination, Endpoint; Determinations, Endpoint; Endpoint Determinations; End Point Determination; Determinations, End Point; End Point Determinations; Point Determinations, End; Endpoint Assay; Assay, Endpoint; Assays, Endpoint; Endpoint Assays; End Point Assay; Assay, End Point; Assays, End Point; End Point Assays; Point Assay, End; Point Assays, End;
Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics;
Tree Number: E05.091.284;
History Note: 2001