Enkephalins - Metabolism
Research News and Information

Sunday, November 22, 2009

Developmental changes in the mRNA expression of neuropeptides and dopamine and glutamate receptors in neonates and adult rats after ventral hippocampal lesion.

2 Jun 2009 BACKGROUND: The neurodevelopment of hippocampus and prefrontal cortex are known to influence different functions in normal and pathological conditions including cognition and sensorimotor functions. The neonatal lesion of the ventral hippocampus ... Read more...

Puberty onset in female rats: relationship with fat intake, ovarian steroids and the peptides, galanin and enkephalin, in the paraventricular and medial preoptic nuclei.

30 May 2009 Puberty is a time of rapid change, including a marked increase in fat consumption and body fat accrual, particularly in females. The mechanisms underlying these changes are unknown. Building on the results obtained in adult rats, the present study ... Read more...

Effect of estradiol on striatal dopamine activity of female hemiparkinsonian monkeys.

13 May 2009 A higher prevalence and incidence of Parkinson's disease is observed in men, and beneficial motor effects of estrogens are observed in parkinsonian women. In rodents, an effect of estradiol on dopamine systems is documented, whereas much less is ... Read more...

Latest indexed articles for 'Enkephalins - Metabolism'

These are the very latest articles for this heading:

• Developmental changes in the mRNA expression of neuropeptides and dopamine and glutamate receptors in neonates and adult rats after ventral hippocampal lesion. 2 Jun 2009
• Puberty onset in female rats: relationship with fat intake, ovarian steroids and the peptides, galanin and enkephalin, in the paraventricular and medial preoptic nuclei. 30 May 2009
• Effect of estradiol on striatal dopamine activity of female hemiparkinsonian monkeys. 13 May 2009
• Differential regulation of prodynophin, c-fos, and serotonin transporter mRNA following withdrawal from a chronic, escalating dose regimen of D-amphetamine. 30 Mar 2009
• D2R striatopallidal neurons inhibit both locomotor and drug reward processes. 6 Mar 2009
• Telencephalic organization in the spotted African Lungfish, Protopterus dolloi: a new cytological model. 25 Feb 2009
• Differential accessibilities of dibasic prohormone processing sites of proenkephalin to the aqueous environment revealed by H-D exchange mass spectrometry. 22 Feb 2009
• Cannabinoid (CB(1)), GABA(A) and GABA(B) receptor subunit changes in the globus pallidus in Huntington's disease. 19 Feb 2009
• X chromosome number causes sex differences in gene expression in adult mouse striatum. 30 Jan 2009
• Intrathecal transplantation of autologous macrophages genetically modified to secrete proenkephalin ameliorated hyperalgesia and allodynia following peripheral nerve injury in rats. 28 Jan 2009
• Striatal alterations of secretogranin-1, somatostatin, prodynorphin, and cholecystokinin peptides in an experimental mouse model of Parkinson disease. 6 Jan 2009
• Glycosyl-enkephalins: synthesis and binding at the mu, delta & kappa opioid receptors. Antinociception in mice. 30 Dec 2008
• Development of mu/delta opioid ligands: enkephalin analogues containing 4-anilidopiperidine moiety. 30 Dec 2008
• Protection conferred by Corticotropin-releasing hormone in rat primary cortical neurons against chemical ischemia involves opioid receptor activation. 28 Dec 2008
• Alterations of prodynorphin gene expression in the rat mesocorticolimbic system during heroin self-administration. 8 Dec 2008
• Dopamine D3 receptor stimulation underlies the development of L-DOPA-induced dyskinesia in animal models of Parkinson's disease. 7 Dec 2008
• The pro-nociceptive effects of remifentanil or surgical injury in mice are associated with a decrease in delta-opioid receptor mRNA levels: Prevention of the nociceptive response by on-site delivery of enkephalins. 3 Dec 2008
• Effect of methamphetamine neurotoxicity on learning-induced Arc mRNA expression in identified striatal efferent neurons. 29 Nov 2008
• Changes in prodynorphin gene expression and neuronal morphology in the hypothalamus of postmenopausal women. 29 Nov 2008
• Paucity of enkephalin production in neostriatal striosomal neurons: analysis with preproenkephalin-green fluorescent protein transgenic mice. 30 Oct 2008

See a longer list of these articles.

Technical information about 'Enkephalins'

Definition: One of the three major families of endogenous opioid peptides. The enkephalins are pentapeptides that are widespread in the central and peripheral nervous systems and in the adrenal medulla.

Registry Number: 0

Descriptor UI: D004745

Alternative terms: Enkephalins; Enkephalin;

Related Mesh Headings: Receptors, Opioid;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Neurotransmitter Agents;

Tree Number: D12.644.400.575.281; D12.644.468.281; D12.776.641.650.575.281;

History Note: 83(Aug 77); was see under ENDORPHINS Aug 1977-82

Technical Notes: general or unspecified; prefer specifics