Enkephalins
Research News and Information

Monday, November 23, 2009

The SAAP force field: development of the single amino acid potentials for 20 proteinogenic amino acids and Monte Carlo molecular simulation for short peptides.

29 Sep 2009 Molecular simulation by using force field parameters has been widely applied in the fields of peptide and protein research for various purposes. We recently proposed a new all-atom protein force field, called the SAAP force field, which utilizes ... Read more...

Effects of early vs. late initiation of levodopa treatment in hemiparkinsonian rats.

25 Aug 2009 We investigated the effect of early vs. late initiation of levodopa treatment on dyskinetic movements, rotational behavior and molecular markers in hemiparkinsonian rats. Male Sprague-Dawley rats received a unilateral 6-hydroxydopamine (6-OHDA) ... Read more...

Modulation of MDMA-induced behavioral and transcriptional effects by the delta opioid antagonist naltrindole in mice.

29 Jun 2009 The delta opioid system is involved in the behavioral effects of various drugs of abuse. However, only a few studies have focused on the possible interactions between the opioid system and the effects of 3,4-methylenedioxymethamphetamine (MDMA). In ... Read more...

Latest indexed articles for 'Enkephalins'

These are the very latest articles for this heading:

• The SAAP force field: development of the single amino acid potentials for 20 proteinogenic amino acids and Monte Carlo molecular simulation for short peptides. 29 Sep 2009
• Effects of early vs. late initiation of levodopa treatment in hemiparkinsonian rats. 25 Aug 2009
• Modulation of MDMA-induced behavioral and transcriptional effects by the delta opioid antagonist naltrindole in mice. 29 Jun 2009
• Prodynorphin gene deficiency potentiates nalbuphine-induced behavioral sensitization and withdrawal syndrome in mice. 23 Jun 2009
• Developmental changes in the mRNA expression of neuropeptides and dopamine and glutamate receptors in neonates and adult rats after ventral hippocampal lesion. 2 Jun 2009
• Effects of prodynorphin deletion on striatal dopamine in mice during normal aging and in response to MPTP. Jun 2009
• Puberty onset in female rats: relationship with fat intake, ovarian steroids and the peptides, galanin and enkephalin, in the paraventricular and medial preoptic nuclei. 30 May 2009
• Gene polymorphisms in prodynorphin (PDYN) are associated with episodic memory in the elderly. 24 May 2009
• Effect of estradiol on striatal dopamine activity of female hemiparkinsonian monkeys. 13 May 2009
• Enkephalin derivative, cyclo[Nepsilon,Nbeta-carbonyl-D-Lys2, Dap5] enkephalinamide (cUENK6), induces a highly potent antinociception in rats. 16 Apr 2009
• delta-Opioid receptor-stimulated Akt signaling in neuroblastoma x glioma (NG108-15) hybrid cells involves receptor tyrosine kinase-mediated PI3K activation. 8 Apr 2009
• N-(ureidoethyl)amides of cyclic enkephalin analogs. 30 Mar 2009
• Endogenous kappa opioid activation mediates stress-induced deficits in learning and memory. 30 Mar 2009
• Differential regulation of prodynophin, c-fos, and serotonin transporter mRNA following withdrawal from a chronic, escalating dose regimen of D-amphetamine. 30 Mar 2009
• Linear and accurate quantitation of proenkephalin-derived peptides by isotopic labeling with internal standards and mass spectrometry. 12 Mar 2009
• Delta opioid receptor-mediated immunoregulatory role of methionine-enkephalin in freshwater teleost Channa punctatus (Bloch.). 11 Mar 2009
• D2R striatopallidal neurons inhibit both locomotor and drug reward processes. 6 Mar 2009
• An association of prodynorphin polymorphisms and opioid dependence in females in a Chinese population. 3 Mar 2009
• Telencephalic organization in the spotted African Lungfish, Protopterus dolloi: a new cytological model. 25 Feb 2009
• Differential accessibilities of dibasic prohormone processing sites of proenkephalin to the aqueous environment revealed by H-D exchange mass spectrometry. 22 Feb 2009

See a longer list of these articles.

Technical information about 'Enkephalins'

Definition: One of the three major families of endogenous opioid peptides. The enkephalins are pentapeptides that are widespread in the central and peripheral nervous systems and in the adrenal medulla.

Registry Number: 0

Descriptor UI: D004745

Alternative terms: Enkephalins; Enkephalin;

Related Mesh Headings: Receptors, Opioid;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Neurotransmitter Agents;

Tree Number: D12.644.400.575.281; D12.644.468.281; D12.776.641.650.575.281;

History Note: 83(Aug 77); was see under ENDORPHINS Aug 1977-82

Technical Notes: general or unspecified; prefer specifics