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Enzyme-Linked Immunosorbent Assay
Research News and Information
Definition of 'Enzyme-Linked Immunosorbent Assay'An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed. |
Saturday, November 21, 2009
16 Dec 2009
This longitudinal study assessed the influence of post-transplant clinical and therapeutic variables in 50 kidney transplant recipients aged 2-19 yr receiving a triple immunosuppressive regimen consisting of cyclosporine microemulsion (CsA), ... Read more...
29 Nov 2009
For patients with brain tumors identification of diagnostic and prognostic markers in easy accessible biological material, such as plasma or cerebrospinal fluid (CSF), would greatly facilitate patient management. MIC-1/GDF15 (growth differentiation ... Read more...
13 Nov 2009
Gastric cancer (GC) is 1 of the most common human cancers. Early detection remains the most promising approach to improving long-term survival of patients with GC. We previously performed Serial Analysis of Gene Expression (SAGE) on 4 primary GCs ... Read more...
Latest indexed articles for 'Enzyme-Linked Immunosorbent Assay'
These are the very latest articles for this heading:
- Longitudinal evaluation of mycophenolic acid pharmacokinetics in pediatric kidney transplant recipients. The role of post-transplant clinical and therapeutic variables.
16 Dec 2009 - Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome.
29 Nov 2009 - Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients.
13 Nov 2009 - Distinct progression-associated expression of tumor and stromal MMPs in HaCaT skin SCCs correlates with onset of invasion.
13 Nov 2009 - Clinical and biological significance of CXCR5 expressed by prostate cancer specimens and cell lines.
13 Nov 2009 - Effect of neutralizing antibodies on biomarker responses to interferon beta: the INSIGHT study.
Nov 2009 - Serum soluble interleukin-2 receptor, beta2-microglobulin, lactate dehydrogenase and erythrocyte sedimentation rate in children with Hodgkin's lymphoma.
30 Oct 2009 - New alternative vaccine component against mycobacterium tuberculosis--heat shock protein 16.3 or its T-cell epitope.
30 Oct 2009 - Identification of Rv2041c, a novel immunogenic antigen from Mycobacterium tuberculosis with serodiagnostic potential.
30 Oct 2009 - Overexpression of Bcl-XL in human neural stem cells promotes graft survival and functional recovery following transplantation in spinal cord injury.
30 Oct 2009 - A confirmation study of Russian and Ukrainian data on effects of 2450 MHz microwave exposure on immunological processes and teratology in rats.
30 Oct 2009 - Quantification of radiation-induced single-strand breaks in plasmid DNA using a TUNEL/ELISA-based assay.
30 Oct 2009 - Dendritic cell transfected with secondary lymphoid-tissue chemokine and/or interleukin-2 gene-enhanced cytotoxicity of T-lymphocyte in human bladder tumor cell S in vitro.
30 Oct 2009 - Upregulated p27kip1 can downregulate survivin expression and inhibit telomerase activity in gastric carcinoma cells.
30 Oct 2009 - Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage.
21 Oct 2009 - Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain.
16 Oct 2009 - Erythropoietin to augment myocardial salvage induced by coronary thrombolysis in patients with ST segment elevation acute myocardial infarction.
13 Oct 2009 - TOB suppresses breast cancer tumorigenesis.
13 Oct 2009 - Affinity-based screening of peptides recognizing assembly states of self-assembling peptide nanomaterials.
12 Oct 2009 - Protein phosphatase 1 regulates the histone code for long-term memory.
12 Oct 2009
See a longer list of these articles.
Technical information about 'Enzyme-Linked Immunosorbent Assay'
Definition: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
Descriptor UI: D004797
Alternative terms: Enzyme-Linked Immunosorbent Assay; Assay, Enzyme-Linked Immunosorbent; Assays, Enzyme-Linked Immunosorbent; Enzyme Linked Immunosorbent Assay; Enzyme-Linked Immunosorbent Assays; Immunosorbent Assay, Enzyme-Linked; Immunosorbent Assays, Enzyme-Linked; ELISA;
Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics;
Tree Number: E01.450.495.410.350.200; E01.450.495.410.380.200; E01.450.495.435.400.170; E05.478.594.410.350.170; E05.478.594.410.380.360; E05.478.594.430.400.170; E05.601.495.350.170; E05.601.495.380.360;
History Note: 86(77); was see under IMMUNOENZYME TECHNIQUES 1977-85
Technical Notes: NIM; IMMUNOSORBENTS is also available