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Enzyme-Linked Immunosorbent Assay
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Definition of 'Enzyme-Linked Immunosorbent Assay'

An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.

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Saturday, November 21, 2009

Longitudinal evaluation of mycophenolic acid pharmacokinetics in pediatric kidney transplant recipients. The role of post-transplant clinical and therapeutic variables.

16 Dec 2009 This longitudinal study assessed the influence of post-transplant clinical and therapeutic variables in 50 kidney transplant recipients aged 2-19 yr receiving a triple immunosuppressive regimen consisting of cyclosporine microemulsion (CsA), ... Read more...


Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome.

29 Nov 2009 For patients with brain tumors identification of diagnostic and prognostic markers in easy accessible biological material, such as plasma or cerebrospinal fluid (CSF), would greatly facilitate patient management. MIC-1/GDF15 (growth differentiation ... Read more...


Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients.

13 Nov 2009 Gastric cancer (GC) is 1 of the most common human cancers. Early detection remains the most promising approach to improving long-term survival of patients with GC. We previously performed Serial Analysis of Gene Expression (SAGE) on 4 primary GCs ... Read more...

 

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Technical information about 'Enzyme-Linked Immunosorbent Assay'

Definition: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.

Descriptor UI: D004797

Alternative terms: Enzyme-Linked Immunosorbent Assay; Assay, Enzyme-Linked Immunosorbent; Assays, Enzyme-Linked Immunosorbent; Enzyme Linked Immunosorbent Assay; Enzyme-Linked Immunosorbent Assays; Immunosorbent Assay, Enzyme-Linked; Immunosorbent Assays, Enzyme-Linked; ELISA;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics;

Tree Number: E01.450.495.410.350.200; E01.450.495.410.380.200; E01.450.495.435.400.170; E05.478.594.410.350.170; E05.478.594.410.380.360; E05.478.594.430.400.170; E05.601.495.350.170; E05.601.495.380.360;

History Note: 86(77); was see under IMMUNOENZYME TECHNIQUES 1977-85

Technical Notes: NIM; IMMUNOSORBENTS is also available

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