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Enzymes - Chemistry
Research News and Information
Definition of 'Enzymes'Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified. Common names: Enzymes; Biocatalysts |
Saturday, November 21, 2009
12 Oct 2009 
In order to model the syn disposition of histidine residues in carboxylate-bridged non-heme diiron enzymes, we prepared a new dinucleating ligand, H(2)BPG(2)DEV, that provides this geometric feature. The ligand incorporates biologically relevant ... Read more...
Automated scaffold selection for enzyme design.
29 Sep 2009 A major goal of computational protein design is the construction of novel functions on existing protein scaffolds. There the first question is which scaffold is suitable for a specific reaction. Given a set of catalytic residues and their spatial ... Read more...
29 Sep 2009 When several models are proposed for one and the same process, experimental design techniques are available to design optimal discriminatory experiments. However, because the experimental design techniques are model-based, it is important that the ... Read more...
Latest indexed articles for 'Enzymes - Chemistry'
These are the very latest articles for this heading:
- Modeling the syn disposition of nitrogen donors in non-heme diiron enzymes. Synthesis, characterization, and hydrogen peroxide reactivity of diiron(III) complexes with the syn N-donor ligand H2BPG2DEV. 12 Oct 2009
- Automated scaffold selection for enzyme design. 29 Sep 2009
- A kernel-based method to determine optimal sampling times for the simultaneous estimation of the parameters of rival mathematical models. 29 Sep 2009
- Enzyme millisecond conformational dynamics do not catalyze the chemical step. 23 Sep 2009
- Three-dimensional structural view of the central metabolic network of Thermotoga maritima. 16 Sep 2009
- Metallotherapeutics: novel strategies in drug design. 5 Sep 2009
- Mixed layers of sodium caseinate + dextran sulfate: influence of order of addition to oil-water interface. 30 Aug 2009
- Nanoreactors for pH controlled sequential activity switching in multistep enzymatic processes. 30 Aug 2009
- Multienzyme complexes and hydrogen transfer: the work of Perry Frey.
19 Aug 2009 - Next generation chemical proteomic tools for rapid enzyme profiling. 16 Aug 2009
- Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin. 11 Aug 2009
- Design of functional metalloproteins. 11 Aug 2009
- Structure-function relationships of anaerobic gas-processing metalloenzymes. 11 Aug 2009
- Metalloproteins. 11 Aug 2009
- Divergent regulation of the key enzymes of polyamine metabolism by chiral alpha-methylated polyamine analogues. 11 Aug 2009
- Cubane-type Co4S4 clusters: synthesis, redox series, and magnetic ground states. 10 Aug 2009
- Uses and production of chiral 3-hydroxy-gamma-butyrolactones and structurally related chemicals. 2 Aug 2009
- Conjugated polyelectrolytes as new platforms for drug screening. Aug 2009
- A toolbox approach to high-throughput TR-FRET-based SUMOylation and DeSUMOylation assays. 30 Jul 2009
- Directed evolution drives the next generation of biocatalysts. 30 Jul 2009
See a longer list of these articles.
Technical information about 'Enzymes'
Definition: Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified.
Registry Number: 0
Descriptor UI: D004798
Alternative terms: Enzymes; Biocatalysts;
Related Mesh Headings: Substrate Specificity;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;
Tree Number: D08.811;
Online Note: pre-explosion = ENZYMES (PX)
Technical Notes: general only: avoid; prefer specific enzyme or / enzymol: Manual 19.7+, 19.8.30; policy: Manual 25.18+; SUBSTRATE SPECIFICITY, restricted to enzymes, is available; ENZYME TESTS, CLINICAL is available for measuring the level of a specific enzyme in the diagnosis of a disease; ENZYME ACTIVATION, ENZYME REPRESSION, ENZYME SATABILITY are also available; ENZYME INDUCTION: coordinate with specific enzyme / biosyn