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Epilepsy
Research News and Information
Definition of 'Epilepsy'A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) |
Saturday, November 21, 2009
13 Dec 2009 
PURPOSE: Vagus nerve stimulation (VNS) is used increasingly as adjunctive therapy for refractory epilepsy. Studies of VNS in children report mainly seizure frequency reduction as a measure of efficacy and clinical details are often scanty. We report ... Read more...
Prevalence of psychopathology in childhood epilepsy: categorical and dimensional measures.
17 Nov 2009 Few studies have utilized both categorical and dimensional measures of psychopathology in children with epilepsy. We evaluated 173 children (88 males, 85 females; mean age 11.7y [SD 1.8]; range 9-14y) who had epilepsy (generalized 36%, partial 61%) ... Read more...
Gene expression analysis on anterior temporal neocortex of patients with intractable epilepsy.
30 Oct 2009 To elucidate the molecular basis of intractable epilepsy (IE), we used a whole-genome transcriptomic approach to identify genes involved in the pathogenesis of this disease. Using a complementary DNAs microarray representing 4096 human genes, we ... Read more...
Latest indexed articles for 'Epilepsy'
These are the very latest articles for this heading:
- Vagus nerve stimulation for refractory epilepsy in children: More to VNS than seizure frequency reduction. 13 Dec 2009
- Prevalence of psychopathology in childhood epilepsy: categorical and dimensional measures. 17 Nov 2009
- Gene expression analysis on anterior temporal neocortex of patients with intractable epilepsy. 30 Oct 2009
- Martin Brodie: epilepsy expertise and whisky wisdom.
30 Oct 2009 - Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation. 30 Oct 2009
- Array-CGH detection of a de novo 0.7-Mb deletion in 19p13.13 including CACNA1A associated with mental retardation and epilepsy with infantile spasms. 30 Oct 2009
- Abstracts from the 2009 Annual Meeting of the American Epilepsy Society. December 4-8, 2009. Boston, Massachusetts, USA. 30 Oct 2009
- Astrocyte-neuron interactions: implications for epilepsy. 18 Oct 2009
- Novel susceptibility locus at chromosome 6q16.3-22.31 in a family with GEFS+. 18 Oct 2009
- Sequential processing of lexical, grammatical, and phonological information within Broca's area. 14 Oct 2009
- Neuroscience. The speaking brain. 14 Oct 2009
- [Drug-resistant epilepsy] 6 Oct 2009
- Intracranial EEG reveals a time- and frequency-specific role for the right inferior frontal gyrus and primary motor cortex in stopping initiated responses. 5 Oct 2009
- mTOR signaling in epileptogenesis: too much of a good thing? 5 Oct 2009
- Hughlings Jackson's suggestion for the treatment of epilepsy. 4 Oct 2009
- Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations. 29 Sep 2009
- Neurology in the elderly: more trials urgently needed. 29 Sep 2009
- Epilepsy in later life. 29 Sep 2009
- Epilepsy: synapses stuck in childhood. 29 Sep 2009
- Effect of CYP3A5*3 genotype on serum carbamazepine concentrations at steady-state in Korean epileptic patients. 29 Sep 2009
See a longer list of these articles.
Technical information about 'Epilepsy'
Definition: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
Descriptor UI: D004827
Alternative terms: Epilepsy; Epilepsies; Seizure Disorder; Seizure Disorders; Seizures, Epileptic; Epileptic Seizures; Epileptic Seizure; Seizure, Epileptic; Single Seizure; Seizure, Single; Seizures, Single; Single Seizures; Epilepsy, Cryptogenic; Cryptogenic Epilepsies; Cryptogenic Epilepsy; Epilepsies, Cryptogenic; Aura; Auras; Awakening Epilepsy; Epilepsy, Awakening;
Related Mesh Headings: Seizures;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C10.228.140.490;
Technical Notes: GEN or unspecified; prefer specifics