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Epinephrine - Metabolism
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Definition of 'Epinephrine'

The active sympathomimetic hormone from the adrenal medulla in most species. It stimulates both the alpha- and beta- adrenergic systems, causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels. It is used in asthma and cardiac failure and to delay absorption of local anesthetics.

Common names: Epinephrine; 4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol; Adrenaline; Epifrin; Epitrate; Adrenaline Bitartrate; Epinephrine Hydrogen Tartrate; Epinephrine Bitartrate; Lyophrin; Micronefrin; Micronephrine; Racepinephrine; Racemic Epinephrine; Epinephrine, Racemic; Vaponefrin

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Sunday, November 22, 2009

A case of extreme hemodynamic lability and hypocalcemia.

30 Aug 2009 An epinephrine-secreting pheochromocytoma can present with a confusing picture of hemodynamic lability with rapid fluctuations between hypo- and hypertension. They are challenging to manage and diagnose. We herein present the case of a 44-year-old ... Read more...


Perioperative management of a child with von Willebrand disease undergoing surgical repair of craniosynostosis: looking at unusual targets.

30 Aug 2009 We report the successful management of a craniosynostosis repair in a child with severe Type I von Willebrand disease diagnosed during the preoperative assessment and treated by coagulation factor VIII and ristocetin cofactor. Collaboration among ... Read more...


Nicotinic receptor-associated modulation of stimulatory and inhibitory neurotransmitters in NNK-induced adenocarcinoma of the lungs and pancreas.

30 Jul 2009 Small airway-derived pulmonary adenocarcinoma (PAC) and pancreatic ductal adenocarcinoma (PDAC) are among the most common human cancers and smoking is a risk factor for both. Emerging research has identified cAMP signalling stimulated by the stress ... Read more...

 

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Technical information about 'Epinephrine'

Definition: The active sympathomimetic hormone from the adrenal medulla in most species. It stimulates both the alpha- and beta- adrenergic systems, causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels. It is used in asthma and cardiac failure and to delay absorption of local anesthetics.

Chemical name: 1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, (R)-

Registry Number: 51-43-4

Descriptor UI: D004837

Alternative terms: Epinephrine; 4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol; Adrenaline; Epifrin; Epitrate; Adrenaline Bitartrate; Epinephrine Hydrogen Tartrate; Epinephrine Bitartrate; Lyophrin; Micronefrin; Micronephrine; Racepinephrine; Racemic Epinephrine; Epinephrine, Racemic; Vaponefrin; Adrenaline Hydrochloride; Hydrochloride, Adrenaline; Medihaler-Epi;

Related Mesh Headings: Receptors, Adrenergic;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Mydriatics; Sympathomimetics; Vasoconstrictor Agents; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic Agonists; Bronchodilator Agents;

Tree Number: D02.033.100.291.310; D02.092.063.291.310; D02.092.211.215.311.461; D02.092.311.461;

Technical Notes: /biosyn /physiol permitted

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