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Epinephrine
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Definition of 'Epinephrine'

The active sympathomimetic hormone from the adrenal medulla in most species. It stimulates both the alpha- and beta- adrenergic systems, causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels. It is used in asthma and cardiac failure and to delay absorption of local anesthetics.

Common names: Epinephrine; 4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol; Adrenaline; Epifrin; Epitrate; Adrenaline Bitartrate; Epinephrine Hydrogen Tartrate; Epinephrine Bitartrate; Lyophrin; Micronefrin; Micronephrine; Racepinephrine; Racemic Epinephrine; Epinephrine, Racemic; Vaponefrin

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Sunday, November 22, 2009

When drugs disappear from the patient: elimination of intravenous medication by hemodiafiltration.

30 Oct 2009 Twenty-three hours after heart transplantation, life-threatening acute right heart failure was diagnosed in a patient requiring continuous venovenous hemodiafiltration (CVVHDF). Increasing doses of catecholamines, sedatives, and muscle relaxants ... Read more...


A hemodynamic profile for consciousness during cardiopulmonary resuscitation.

30 Oct 2009 We report the quantification of a hemodynamic profile sufficient to support consciousness during cardiopulmonary resuscitation. A 62-yr-old man experienced cardiac arrest while being evaluated for heart failure after heart transplantation. During ... Read more...


Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo.

3 Oct 2009 Platelet activation at a site of vascular injury is essential for the arrest of bleeding; however, excessive platelet activation at a site of arterial damage can result in the unwarranted formation of arterial thrombi, precipitating acute myocardial ... Read more...

 

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Technical information about 'Epinephrine'

Definition: The active sympathomimetic hormone from the adrenal medulla in most species. It stimulates both the alpha- and beta- adrenergic systems, causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels. It is used in asthma and cardiac failure and to delay absorption of local anesthetics.

Chemical name: 1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, (R)-

Registry Number: 51-43-4

Descriptor UI: D004837

Alternative terms: Epinephrine; 4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol; Adrenaline; Epifrin; Epitrate; Adrenaline Bitartrate; Epinephrine Hydrogen Tartrate; Epinephrine Bitartrate; Lyophrin; Micronefrin; Micronephrine; Racepinephrine; Racemic Epinephrine; Epinephrine, Racemic; Vaponefrin; Adrenaline Hydrochloride; Hydrochloride, Adrenaline; Medihaler-Epi;

Related Mesh Headings: Receptors, Adrenergic;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Mydriatics; Sympathomimetics; Vasoconstrictor Agents; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic Agonists; Bronchodilator Agents;

Tree Number: D02.033.100.291.310; D02.092.063.291.310; D02.092.211.215.311.461; D02.092.311.461;

Technical Notes: /biosyn /physiol permitted

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