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Escherichia coli - Genetics
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Definition of 'Escherichia coli'

A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.

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Monday, November 23, 2009

Escherichia coli glycogen metabolism is controlled by the PhoP-PhoQ regulatory system at submillimolar environmental Mg2+ concentrations, and is highly interconnected with a wide variety of cellular processes.

21 Oct 2009 Using the Keio collection of gene-disrupted mutants of Escherichia coli, we have recently carried out a genome-wide screening of the genes affecting glycogen metabolism. Among the mutants identified in the study, Delta mgtA, Delta phoP and Delta ... Read more...


An oxygen-sensing diguanylate cyclase and phosphodiesterase couple for c-di-GMP control.

18 Oct 2009 A commonly observed coupling of sensory domains to GGDEF-class diguanylate cyclases and EAL-class phosphodiesterases has long suggested that c-di-GMP synthesizing and degrading enzymes sense environmental signals. Nevertheless, relatively few signal ... Read more...


Reduced capacity of alternative sigmas to melt promoters ensures stringent promoter recognition.

13 Oct 2009 In bacteria, multiple sigmas direct RNA polymerase to distinct sets of promoters. Housekeeping sigmas direct transcription from thousands of promoters, whereas most alternative sigmas are more selective, recognizing more highly conserved promoter ... Read more...

 

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Technical information about 'Escherichia coli'

Definition: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.

Descriptor UI: D004926

Alternative terms: Escherichia coli; E coli; Diffusely Adherent Escherichia coli; Diffusely Adherent E. coli; Enteroinvasive Escherichia coli; Enteroinvasive E. coli; Alkalescens-Dispar Group; Enteroaggregative Escherichia coli; Enteroaggregative E. coli; EAggEC;

Related Mesh Headings: Escherichia coli Proteins;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; genetics; growth & development; immunology; isolation & purification; metabolism; pathogenicity; physiology; radiation effects; ultrastructure; chemistry; virology;

Tree Number: B03.440.450.425.325.300; B03.660.250.150.180.100;

Online Note: use SHIGELLA to search ALKALESCENS-DISPAR GROUP 1974; use ENTEROBACTERIACEAE 1966-73

History Note: ALKALESCENS-DISPAR GROUP was heading 1975-96 (see under ESCHERICHIA 1975-90); was see under SHIGELLA 1974; was see under ENTEROBACTERIACEAE 1963-73 (Prov 1963-67)

Technical Notes: not for "coliform bacillus" ( = COLIFORM BACILLI see ENTEROBACTERIACEAE); note specific strains; infection = ESCHERICHIA COLI INFECTIONS

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