Esophageal Neoplasms - Genetics
Research News and Information

Thursday, March 18, 2010

IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas.

29 Nov 2009 The mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) encodes a protein that plays a critical role in tumor suppression, in part by modulating bioavailability of a potent mitogen, insulin-like growth factor-2 (IGF2). We tested ... Read more...

Prostaglandin E(2) promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells.

29 Nov 2009 Overexpression of cyclooxygenase-2 (COX-2) and elevation of its derivative prostaglandin E(2) (PGE(2)) are implicated in human esophageal squamous cell carcinoma. The expression of c-Myc, an oncogenic transcription factor, is also upregulated in ... Read more...

Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma.

13 Nov 2009 Barrett's esophagus (BE) is a metaplastic condition caused by chronic gastroesophageal reflux which represents an early step in the development of esophageal adenocarcinoma (EAC). Single-nucleotide polymorphism microarray (SNP-chip) analysis is a ... Read more...

Latest indexed articles for 'Esophageal Neoplasms - Genetics'

These are the very latest articles for this heading:

• IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas. 29 Nov 2009
• Prostaglandin E(2) promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells. 29 Nov 2009
• Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma. 13 Nov 2009
• Insulin-like growth factor type I receptor gene expression and obesity in esophageal adenocarcinoma. 30 Oct 2009
• Radiofrequency ablation and dilated columnar-lined esophagus. 29 Sep 2009
• XRCC1 codon 280 and ERCC2 codon 751 polymorphisms and risk of esophageal squamous cell carcinoma in a Chinese population. 29 Sep 2009
• Regulation of CDX2 expression in esophageal adenocarcinoma. 29 Sep 2009
• Cyclooxygenase-2 Gly587Arg variant is associated with differential enzymatic activity and risk of esophageal squamous-cell carcinoma. 29 Sep 2009
• Expression profiles of early esophageal squamous cell carcinoma by cDNA microarray. 29 Sep 2009
• A gene expression model of intrinsic tumor radiosensitivity: prediction of response and prognosis after chemoradiation. 29 Sep 2009
• Expression of esophageal cancer related gene 4 (ECRG4), a novel tumor suppressor gene, in esophageal cancer and its inhibitory effect on the tumor growth in vitro and in vivo. 29 Sep 2009
• [Upper G.I. cancer: the esophagus and stomach. II. The current status of comprehensive gene analysis of esophageal cancer] 30 Aug 2009
• Barrett's: do we still need goblet cells for diagnosis? 30 Aug 2009
• Genetic modulation of ADH1B and ALDH2 polymorphisms with regard to alcohol and tobacco consumption for younger aged esophageal squamous cell carcinoma diagnosis. 30 Aug 2009
• XRCC1 gene polymorphisms and esophageal squamous cell carcinoma risk in Chinese population: A meta-analysis of case-control studies. 30 Aug 2009
• Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma. 15 Aug 2009
• Cisplatin pharmacogenetics, DNA repair polymorphisms, and esophageal cancer outcomes. 30 Jul 2009
• The feasibility of using biopsy samples from esophageal cancer for comprehensive gene expression profiling. 30 Jul 2009
• The presence of aberrant DNA methylation in noncancerous esophageal mucosae in association with smoking history: a target for risk diagnosis and prevention of esophageal cancers. 30 Jul 2009
• ERBB2 suppression decreases cell growth via apoptosis in gastrointestinal adenocarcinomas. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Esophageal Neoplasms'

Definition: Tumors or cancer of the ESOPHAGUS.

Descriptor UI: D004938

Alternative terms: Esophageal Neoplasms; Esophageal Neoplasm; Neoplasm, Esophageal; Neoplasms, Esophageal; Esophagus Neoplasm; Esophagus Neoplasms; Neoplasm, Esophagus; Neoplasms, Esophagus; Cancer of Esophagus; Cancer of the Esophagus; Esophagus Cancer; Cancer, Esophagus; Cancers, Esophagus; Esophagus Cancers; Esophageal Cancer; Cancer, Esophageal; Cancers, Esophageal; Esophageal Cancers;

Allowable Qualifiers: blood; blood supply; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; secondary; secretion; surgery; therapy; ultrastructure; urine; veterinary; ultrasonography; chemistry; virology;

Tree Number: C04.588.274.476.205; C04.588.443.353; C06.301.371.205; C06.405.117.430; C06.405.249.205;

Technical Notes: coord IM with histol type of neopl (IM)